S
Sybren L. Meijer
Researcher at University of Amsterdam
Publications - 444
Citations - 22776
Sybren L. Meijer is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Breast cancer & Sentinel node. The author has an hindex of 71, co-authored 425 publications receiving 20559 citations. Previous affiliations of Sybren L. Meijer include Vanderbilt University Medical Center & VU University Amsterdam.
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Journal ArticleDOI
Efficacy of MRI and Mammography for Breast-Cancer Screening in Women with a Familial or Genetic Predisposition
Mieke Kriege,Cecile T. M. Brekelmans,Carla Boetes,Peter E. Besnard,H. M. Zonderland,Inge Marie Obdeijn,Radu A. Manoliu,Theo Kok,Hans Peterse,Madeleine M.A. Tilanus-Linthorst,Sara H. Muller,Sybren L. Meijer,Jan C. Oosterwijk,Louk V.A.M. Beex,Rob A. E. M. Tollenaar,Harry J. de Koning,Emiel J. Th. Rutgers,Jan G. M. Klijn +17 more
TL;DR: MRI appears to be more sensitive than mammography in detecting tumors in women with an inherited susceptibility to breast cancer.
Journal ArticleDOI
Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
Jochem H. Bernink,Charlotte P. Peters,Marius Munneke,Anje A. te Velde,Sybren L. Meijer,Kees Weijer,Hulda S. Hreggvidsdottir,Sigrid E.M. Heinsbroek,Nicolas Legrand,Nicolas Legrand,Christianne J. Buskens,Willem A. Bemelman,Jenny Mjösberg,Jenny Mjösberg,Hergen Spits +14 more
TL;DR: The frequency of the ILC1 subset was much higher in inflamed intestine of people with Crohn's disease, which indicated a role for these IFN-γ-producing I LC1 cells in the pathogenesis of gut mucosal inflammation.
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Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial
Henk H. Hartgrink,C.J.H. van de Velde,Hein Putter,Johannes J. Bonenkamp,E. Klein Kranenbarg,I. Songun,K. Welvaart,J.H.J.M. van Krieken,Sybren L. Meijer,J. T. Plukker,P. van Elk,Huug Obertop,D. J. Gouma,J. J. B. van Lanschot,C.W. Taat,P. W. de Graaf,M.F. von Meyenfeldt,H. W. Tilanus,M. Sasako +18 more
TL;DR: Overall, extended lymph node dissection as defined in this study generated no long-term survival benefit, and the associated higher postoperative mortality offsets its long- term effect in survival.
Journal ArticleDOI
Sentinel Lymph Node Biopsy in Breast Cancer: Guidelines and Pitfalls of Lymphoscintigraphy and Gamma Probe Detection
Paul J. Borgstein,Rik Pijpers,E.F.I. (Emile) Comans,Paul J. van Diest,Rob P.A. Boom,Sybren L. Meijer +5 more
TL;DR: Biopsy of the Sentinel node (SN) is a highly accurate, minimally invasive method of staging patients with breast cancer and can substantially reduce the morbidity and costs of surgical treatment by avoiding unnecessary ALND in the majority of patients.
Journal ArticleDOI
Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial
K. Nadine Phoa,Frederike G. Van Vilsteren,Bas L. Weusten,Raf Bisschops,Erik J. Schoon,Krish Ragunath,Grant Fullarton,Massimiliano di Pietro,Narayanasamy Ravi,Mike Visser,G. Johan A. Offerhaus,Cees A. Seldenrijk,Sybren L. Meijer,Fiebo J.W. ten Kate,Jan G.P. Tijssen,Jacques J. Bergman +15 more
TL;DR: Radiofrequency ablation resulted in a reduced risk of neoplastic progression over 3 years of follow-up and the data and safety monitoring board recommended early termination of the trial due to superiority of ablation for the primary outcome and the potential for patient safety issues if the trial continued.