J
John J. Lech
Researcher at Woods Hole Oceanographic Institution
Publications - 2
Citations - 502
John J. Lech is an academic researcher from Woods Hole Oceanographic Institution. The author has contributed to research in topics: Carcinogen & Xenobiotic. The author has an hindex of 2, co-authored 2 publications receiving 496 citations.
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Journal ArticleDOI
Cytochrome P-450 Monooxygenase Systems in Aquatic Species: Carcinogen Metabolism and Biomarkers for Carcinogen and Pollutant Exposure
John J. Stegeman,John J. Lech +1 more
TL;DR: High levels of polynuclear aromatic hydrocarbon (PAH) carcinogens commonly occur in aquatic systems where neoplasms arise in fish and other animals andenzymes that transform PAHs can act in initiatin formation.
Journal ArticleDOI
Relationship between biotransformation and the toxicity and fate of xenobiotic chemicals in fish.
John J. Lech,John R. Bend +1 more
TL;DR: Many of the biotransformation reactions which have been described for xenobiotic substances in mammals have been demonstrated in fish in both in vitro and in vivo experiments, showing significant effects on the toxicity and residue dynamics of selected chemicals.