John K. McGee

TL;DR: Results of studies conducted to identify constituents responsible for the acute lung injury induced by residual oil fly ash (ROFA) and to assess physical-chemical factors that influence the pulmonary toxicity of these constituents provide direct evidence for the role of soluble transition metals in the pulmonary injuryinduced by the combustion emission source particulate, ROFA.

TL;DR: Results suggest that combustion-derived particles did not form a significant fraction of these samples recovered in the immediate aftermath of the destruction of the towers, suggesting that inhalation of high doses of WTC PM2.5 could potentially cause toxic respiratory effects.

TL;DR: ROFA-induced in vivo acute pulmonary inflammation appears to be associated with its water-leachable V content; however, protein leakage appears to have been associated withIts water- Leachable Ni content.

TL;DR: The pulmonary effects induced by exposure of rats to water-based extracts of local ambient PM filters were in good accord with the cross-sectional epidemiologic reports of adverse respiratory health effects in Utah Valley residents.

TL;DR: The hypothesis that the composition of soluble metals and sulfate leached from ROFA, an emission source particle, is critical in the development of airway hyperreactivity and lung injury is reinforced.