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John M. Crawford

Researcher at United States Department of Agriculture

Publications -  7
Citations -  587

John M. Crawford is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: Virus & Influenza A virus subtype H5N1. The author has an hindex of 6, co-authored 6 publications receiving 571 citations.

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Heterogeneity in the haemagglutinin gene and emergence of the highly pathogenic phenotype among recent H5N2 avian influenza viruses from Mexico

TL;DR: Molecular changes in the haemagglutinin (HA)-coding regions and proteolytic cleavage sites from multiple H5N2 subtype viruses isolated during a recent outbreak of avian influenza in central Mexico have been characterized.
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Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes.

TL;DR: When challenged with highly pathogenic strains of the corresponding AI subtypes, the vaccinated birds were completely protected against lethal infection and in some cases exhibited reduced or no cloacal shedding at 3 days postinfection.
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Newcastle disease virus phosphoprotein gene analysis and transcriptional editing in avian cells.

TL;DR: Comparison of the P gene editing sites among the Paramyxovirinae and predicted P gene usage demonstrates that NDV more closely resembles the respiroviruses and morbilliviruses.
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Nucleotide sequence analysis of the Newcastle disease virus nucleocapsid protein gene and phylogenetic relationships among the Paramyxoviridae

TL;DR: Comparison of NDV and avian paramyxovirus 6 separating as a cluster distinct from the Rubulavirus genus provides further support for avianParamyxoviruses being considered for their own genus among the Paramyxovirinae.
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A Novel Carbohydrate Addition Site on the Hemagglutinin Protein of a Highly Pathogenic H7 Subtype Avian Influenza Virus

TL;DR: The data raise the possibility that presence of carbohydrate near the receptor site on the H7 avian influenza virus hemagglutinin may influence virulence.