Showing papers by "John P. Boehmer published in 2019"
TL;DR: A high incidence of CRT nonresponders persists despite good patient selection and LV lead position, but site identification methods have modest sensitivity.
48 citations
TL;DR: The Penn State Heart Assistant, a web-based, tablet computer-accessed, secure application was developed to conduct a proof of concept test, targeting patient self-care activities of heart failure patients including daily medication adherence, weight monitoring, and aerobic activity, suggesting that mobile technology is feasible, acceptable, and has potential for cost-effective opportunities to manage heart failure Patients safely at home.
Abstract: The Penn State Heart Assistant, a web-based, tablet computer-accessed, secure application was developed to conduct a proof of concept test, targeting patient self-care activities of heart failure p...
13 citations
TL;DR: This analysis provides strong evidence that the poor survival associated lower %LV pacing is likely caused by worsening heart failure.
1 citations
TL;DR: There is no current data available on the use of Cardiac Resynchronization Therapy (CRT) in order to wean mechanical circulatory support in patients with cardiac arrest.
1 citations
TL;DR: Larger versus smaller LVEDDIs are associated with a reduction in ACM with CRT-P orCRT-D treatment, and with a more effective reduction inACM/HFH for the combined CRT treatment groups.
Abstract: Objectives This study tested the hypothesis that the extent of left ventricular (LV) eccentric structural remodeling in heart failure with reduced ejection fraction (HFrEF) is directly associated with clinical event responses to cardiac resynchronization therapy (CRT). Background Whether the severity of LV structural remodeling influences CRT treatment effects is unknown. Methods COMPANION (Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure) trial data were analyzed retrospectively. Left ventricular internal dimensions at end diastole indexed by body surface area (LVEDDI) were measured pre-randomization by 2-dimensional echocardiography. LVEDDI values were stratified around the median value of 35 mm/m2, and CRT (including CRT-P [CRT with only pacing capability] and/or CRT-D [CRT with an implantable defibrillator]) treatment effects were assessed and compared by LVEDDI group. Patients assigned to these treatments were compared to those undergoing optimal pharmacologic therapy (OPT) for the outcomes of all-cause mortality (ACM) or ACM and heart-failure hospitalization (ACM/HFH). Results In the LVEDDI ≥35 mm/m2 group (n = 614), CRT vs. OPT was associated with a lower ACM/HFH hazard ratio (HR) (HR: 0.53; 95% confidence interval [CI]: 0.40 to 0.70; p Conclusions Larger versus smaller LVEDDIs are associated with a reduction in ACM with CRT-P or CRT-D treatment, and with a more effective reduction in ACM/HFH for the combined CRT treatment groups.
1 citations