J
John Panelos
Researcher at University of Ioannina
Publications - 19
Citations - 616
John Panelos is an academic researcher from University of Ioannina. The author has contributed to research in topics: Notch signaling pathway & Melanoma. The author has an hindex of 10, co-authored 19 publications receiving 562 citations. Previous affiliations of John Panelos include University of Florence.
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Journal ArticleDOI
Application of a Filtration- and Isolation-by-Size Technique for the Detection of Circulating Tumor Cells in Cutaneous Melanoma
Vincenzo De Giorgi,Pamela Pinzani,Francesca Salvianti,John Panelos,Milena Paglierani,Agata Janowska,Marta Grazzini,Janine Wechsler,Claudio Orlando,Marco Santucci,Torello Lotti,Mario Pazzagli,Daniela Massi +12 more
TL;DR: CTC detection corroborated by suitable molecular characterization may assist in the identification and monitoring of more appropriate therapies in melanoma patients and potentially improves patient management.
Journal ArticleDOI
Primary cutaneous leiomyosarcoma: clinicopathological analysis of 36 cases.
Daniela Massi,Alessandro Franchi,Llucia Alos,Martin G. Cook,Silvana Di Palma,Ana Belén Enguita,Gerardo Ferrara,Dmitry V. Kazakov,Thomas Mentzel,Michal Michal,John Panelos,José Luis Rodríguez-Peralto,Marco Santucci,Gabrina Tragni,Aikaterini Zioga,Angelo Paolo Dei Tos +15 more
TL;DR: It is necessary to consider the role of environmental factors in the development of central giant cell granuloma as a source of disease.
Journal ArticleDOI
Emerging role of Notch signaling in epidermal differentiation and skin cancer.
John Panelos,Daniela Massi +1 more
TL;DR: The pleiotropic roles of the Notch signaling pathway in normal skin homeostasis and differentiation are highlighted and its altered regulation in the tumorigenesis of melanoma and non-melanoma skin cancer is focused on.
Journal ArticleDOI
The Wilms’ tumor suppressor WT1 is associated with melanoma proliferation
Nicole Wagner,Nicole Wagner,John Panelos,Daniela Massi,Kay-Dietrich Wagner,Kay-Dietrich Wagner +5 more
TL;DR: It is shown that WT1 is expressed in malignant melanoma in >80% of the tumor cells, but not in normal skin or benign melanocytic nevi in vivo, which suggests a direct role of WT1 in melanoma proliferation, which might be mediated via Nestin and Zyxin.
Journal ArticleDOI
Inducible nitric oxide synthase expression in melanoma: implications in lymphangiogenesis
Daniela Massi,Maria Caterina De Nisi,Alessandro Franchi,Vasileios Mourmouras,Gianna Baroni,John Panelos,Marco Santucci,Clelia Miracco +7 more
TL;DR: The hypothesis that inducible nitric oxide synthase is implicated not only in blood, but also in lymphatic vascular neoformation in melanoma is supported.