J
Jolanda C. Boxmeer
Researcher at Erasmus University Rotterdam
Publications - 10
Citations - 519
Jolanda C. Boxmeer is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Cobalamin & Homocysteine. The author has an hindex of 9, co-authored 10 publications receiving 442 citations.
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Journal ArticleDOI
Low folate in seminal plasma is associated with increased sperm DNA damage
Jolanda C. Boxmeer,Marij Smit,Elaine Utomo,Johannes C. Romijn,Marinus J.C. Eijkemans,Jan Lindemans,Joop S.E. Laven,Nick S. Macklon,Nick S. Macklon,Eric A.P. Steegers,Régine P.M. Steegers-Theunissen +10 more
TL;DR: Low concentrations of folate in seminal plasma may be detrimental for sperm DNA stability, and associations between vitamin B status, homocysteine, semen parameters, and sperm DNA damage are determined.
Journal ArticleDOI
IVF outcomes are associated with biomarkers of the homocysteine pathway in monofollicular fluid
Jolanda C. Boxmeer,Nick S. Macklon,Jan Lindemans,Nicole G. M. Beckers,Marinus J.C. Eijkemans,Marinus J.C. Eijkemans,Joop S.E. Laven,Eric A.P. Steegers,Régine P.M. Steegers-Theunissen +8 more
TL;DR: An optimal homocysteine pathway in follicular fluid is associated with a better embryo quality and chance of pregnancy.
Journal ArticleDOI
Preconception folic acid treatment affects the microenvironment of the maturing oocyte in humans.
Jolanda C. Boxmeer,R. Montserrate Brouns,Jan Lindemans,Eric A.P. Steegers,Elena Martini,Nick S. Macklon,Nick S. Macklon,Régine P.M. Steegers-Theunissen +7 more
TL;DR: Investigation of the influence of folic acid supplementation on the follicular fluid concentrations of folate and total homocysteine and their relationship to the diameter of the follicle concluded that preconceived women undergoing IVF or intracytoplasmic sperm injection treatment are most at risk of adverse events.
Journal ArticleDOI
Homocysteine metabolism in the pre-ovulatory follicle during ovarian stimulation
Jolanda C. Boxmeer,Régine P.M. Steegers-Theunissen,Jan Lindemans,Mark F. Wildhagen,Elena Martini,Eric A. P. Steegers,Nick S. Macklon,Nick S. Macklon +7 more
TL;DR: This study aims to investigate whether ovarian stimulation deranges the homocysteine pathway thereby affecting the pre-ovulatory follicle, and whether high ovarian follicular fluid tHcy and folate levels may have detrimental effects on follicular development.
Journal ArticleDOI
Seminal plasma cobalamin significantly correlates with sperm concentration in men undergoing IVF or ICSI procedures.
Jolanda C. Boxmeer,Marij Smit,R. F. A. Weber,Jan Lindemans,Johannes C. Romijn,Marinus J.C. Eijkemans,Nick S. Macklon,Régine P.M. Steegers-Theunissen +7 more
TL;DR: It is suggested that folate and cobalamin are transferred from the blood to the male reproductive organs and emphasize the role of cobalamina in spermatogenesis in human.