J
Jon A. Tsai
Researcher at Karolinska Institutet
Publications - 53
Citations - 1359
Jon A. Tsai is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Chemoradiotherapy & Esophagectomy. The author has an hindex of 17, co-authored 52 publications receiving 1125 citations. Previous affiliations of Jon A. Tsai include Karolinska University Hospital.
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Journal ArticleDOI
A randomized clinical trial of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the oesophagus or gastro-oesophageal junction
Fredrik Klevebro,G. Alexandersson von Döbeln,N. Wang,Gjermund Johnsen,Anne-Birgitte Jacobsen,Signe Friesland,Ingunn Hatlevoll,Nils Glenjen,Pehr Lind,Jon A. Tsai,Lars Lundell,Magnus Nilsson +11 more
TL;DR: The addition of radiotherapy to neoadjuvant chemotherapy results in higher histological complete response rate, higher R0 resection rate, and a lower frequency of lymph-node metastases, without significantly affecting survival.
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Meta-analysis of postoperative morbidity and perioperative mortality in patients receiving neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal and gastro-oesophageal junctional cancers.
Koshi Kumagai,Ioannis Rouvelas,Jon A. Tsai,Daniela Mariosa,Fredrik Klevebro,Mats Lindblad,Weimin Ye,Lars Lundell,Magnus Nilsson +8 more
TL;DR: The long‐term survival benefits of neoadjuvant chemotherapy and chemoradiotherapy for oesophageal carcinoma are well established, however, both are burdened by toxicity that could contribute to perioperative morbidity and mortality.
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Morbidity and mortality after surgery for cancer of the oesophagus and gastro-oesophageal junction: A randomized clinical trial of neoadjuvant chemotherapy vs. neoadjuvant chemoradiation.
Fredrik Klevebro,Gjermund Johnsen,Egil Johnson,Asgaut Viste,T. Myrnas,Eva Szabo,Anne-Birgitte Jacobsen,Signe Friesland,Jon A. Tsai,Saga Persson,Mats Lindblad,Lars Lundell,Magnus Nilsson +12 more
TL;DR: There was no significant difference in the incidence of complications between patients randomized to nCT and n CRT, however, complications were significantly more severe after nCRT.
Journal ArticleDOI
Per-oral endoscopic myotomy for achalasia. Are results comparable to laparoscopic Heller myotomy?
TL;DR: POEM seems to be a safe and effective treatment option for achalasia in the short-term perspective; an effect well comparable to LHM.
Journal ArticleDOI
Weak Evidence of Thyrotropin Receptors in Primary Cultures of Human Osteoblast-like Cells
Jon A. Tsai,Annika Janson,E. Bucht,H. Kindmark,C Marcus,André Stark,H. Rawet Zemack,O. Torring +7 more
TL;DR: It is suggested that it is unlikely that circulating TSH plays a physiological role for bone metabolism mediated through osteoblasts, given the low level of expression, specific binding and cAMP signaling.