J
Jon I. Arellano
Researcher at Yale University
Publications - 28
Citations - 2793
Jon I. Arellano is an academic researcher from Yale University. The author has contributed to research in topics: Hippocampal formation & Neocortex. The author has an hindex of 16, co-authored 25 publications receiving 2530 citations. Previous affiliations of Jon I. Arellano include Spanish National Research Council.
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Journal ArticleDOI
Microstructure of the neocortex: Comparative aspects
TL;DR: Differences in cortical areas of the human, rat and mouse probably indicate the evolutionary adaptation of excitatory and inhibitory circuits to particular functions.
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Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies.
TL;DR: For all morphological parameters analyzed, spines exhibited a continuum of variability, without clearly distinguishable subtypes of spines or clear dependence of their morphologies on their distance to the soma.
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Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling
Joshua J. Breunig,Matthew R. Sarkisian,Jon I. Arellano,Yury M. Morozov,Albert E. Ayoub,Sonal Sojitra,Baolin Wang,Richard A. Flavell,Pasko Rakic,Terrence Town +9 more
TL;DR: These organelles are cellular “antennae” critically required to modulate ALNP behavior, and selective targeting of Shh machinery to primary cilia confers to ALNPs the ability to differentially respond to Shh mitogenic signals compared to neighboring cells.
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Synaptically Released Acetylcholine Evokes Ca2+Elevations in Astrocytes in Hippocampal Slices
TL;DR: The results show the existence of cholinergic neuron–astrocyte signaling and suggest that astrocytes are a target of axonal inputs from different brain areas.
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Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release
Antonio M. Persico,Elisa Mengual,Rainald Moessner,Scott F. Hall,Randal S. Revay,Ichiro Sora,Jon I. Arellano,Javier DeFelipe,José Manuel Giménez-Amaya,Monica Conciatori,Ramona Marino,Alfonso Baldi,Simona Cabib,Tiziana Pascucci,George R. Uhl,Dennis L. Murphy,K. Peter Lesch,Flavio Keller +17 more
TL;DR: 5-HTT knock-out mice reveal a nearly complete absence of 5-HT in the cerebral cortex by immunohistochemistry, and of barrels, both at P7 and adulthood, while VMAT2 ko mice, completely lacking activity-dependent vesicular release of monoamines including 5- HT, also show a complete lack of 4-HT, but display largely normal barrel fields.