J
Jon J. Schmuke
Researcher at Monsanto
Publications - 9
Citations - 348
Jon J. Schmuke is an academic researcher from Monsanto. The author has contributed to research in topics: Selectin & Arabidopsis. The author has an hindex of 8, co-authored 9 publications receiving 345 citations.
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Journal ArticleDOI
Application of two-dimensional gel electrophoresis to interrogate alterations in the proteome of gentically modified crops. 3. Assessing unintended effects.
Martin C. Ruebelt,Markus Lipp,Tracey L. Reynolds,Jon J. Schmuke,James D. Astwood,Dean DellaPenna,Karl-Heinz Engel,Klaus Dieter Jany +7 more
TL;DR: An optimized two-dimensional gel electrophoresis method was used as a proteomics approach to investigate insertional and pleiotropic effects on the proteome due to genetic engineering in Arabidopsis.
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Multivalent sialyl-LeX: potent inhibitors of E-selectin-mediated cell adhesion; reagent for staining activated endothelial cells.
Joseph K. Welply,S Z Abbas,Peter Richard Scudder,Jeffery L. Keene,Broschat K,Casnocha S,Gorka C,Christina N. Steininger,Susan C. Howard,Jon J. Schmuke +9 more
TL;DR: SLeX-BSA was found to be an excellent reagent for staining endothelial cells expressing E-selectin and demonstrated a three-order-of-magnitude enhancement of inhibitory activity with the multivalent form of SLeX.
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Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation
Thomas R. Ulich,Susan C. Howard,Daniel G. Remick,Eunhee S. Yi,Tucker Collins,Kaizhi Guo,Songmei Yin,Jeffery L. Keene,Jon J. Schmuke,Christina N. Steininger,Joseph K. Welply,James H. Williams +11 more
TL;DR: In conclusion, E-selectin-mediated adhesion of neutrophils to endothelium appears crucial to the full development of the acute inflammation response and may play a role in the endogenous down-regulation of acute inflammation.
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Selectins as potential targets of therapeutic intervention in inflammatory diseases.
Journal ArticleDOI
Development and evaluation of a Gal4-mediated LUC/GFP/GUS enhancer trap system in Arabidopsis
TL;DR: The Gal4 trap system described here uses the 5XUAS-LUC and 5X UAS rsGFP-GUS as reporters and allows for in planta quantitative screening, including the rapid monitoring for silencing.