J
Jonathan C. T. Carlson
Researcher at Harvard University
Publications - 36
Citations - 2906
Jonathan C. T. Carlson is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Bioorthogonal chemistry. The author has an hindex of 14, co-authored 25 publications receiving 1911 citations. Previous affiliations of Jonathan C. T. Carlson include Hauptman-Woodward Medical Research Institute & University of Minnesota.
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Journal ArticleDOI
COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection.
Hanny Al-Samkari,Rebecca Karp Leaf,Walter H. Dzik,Jonathan C. T. Carlson,Annemarie E. Fogerty,Anem Waheed,Katayoon Goodarzi,Pavan K. Bendapudi,Larissa Bornikova,Shruti Gupta,Shruti Gupta,David E. Leaf,David E. Leaf,David J. Kuter,Rachel P. Rosovsky +14 more
TL;DR: Elevated D-dimer at initial presentation was predictive of coagulation-associated complications during hospitalization and ESR, CRP, fibrinogen, ferritin, and procalcitonin were higher in patients with thrombotic complications than in those without.
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In Vivo Imaging Reveals a Tumor-Associated Macrophage-Mediated Resistance Pathway in anti-PD-1 Therapy
Sean P. Arlauckas,Christopher Garris,Rainer H. Kohler,Maya Kitaoka,Michael F. Cuccarese,Katherine S. Yang,Miles A. Miller,Jonathan C. T. Carlson,Gordon J. Freeman,Robert M. Anthony,Ralph Weissleder,Mikael J. Pittet +11 more
TL;DR: In vivo imaging is used to uncover the fate and activity of aPD-1 mAbs and identify specific Fc/FcγR interactions that can be modulated to improve checkpoint blockade therapy.
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Chemically Controlled Protein Assembly: Techniques and Applications
TL;DR: The study of biological processes has driven the efforts of modern molecular biology to unravel the microscopic capabilities of natural systems and the development of methods that investigate and exploit protein assembly and protein-protein interactions.
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BODIPY–Tetrazine Derivatives as Superbright Bioorthogonal Turn‐on Probes
TL;DR: A new design that intimately connects tetrazine to a BODIPY fluorophore enables exceptionally efficient energy transfer and quenching and triggers a fluorogenic activation up to two orders of magnitude greater than previously described.
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Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging
TL;DR: A series of new ultrafluorogenic probes in the blue-green region of the visible-light spectrum that display fluorescence enhancement exceeding 11,000-fold are developed, which are reported to be the highest brightness enhancements reported for any bioorthogonal fluorogenic dyes.