J
Jonathan Green
Researcher at McGill University
Publications - 1
Citations - 334
Jonathan Green is an academic researcher from McGill University. The author has contributed to research in topics: Gene silencing & Argonaute. The author has an hindex of 1, co-authored 1 publications receiving 310 citations.
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miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
Marc R. Fabian,Maja K Cieplak,Filipp Frank,Masahiro Morita,Masahiro Morita,Jonathan Green,Tharan Srikumar,Bhushan Nagar,Tadashi Yamamoto,Brian Raught,Thomas F. Duchaine,Nahum Sonenberg +11 more
TL;DR: It is shown here that human GW182 independently interacts with the PAN2–PAN3 and CCR4–NOT deadenylase complexes, and serves as both a platform that recruitsdeadenylases and as a deadenyase coactivator that facilitates the removal of the poly(A) tail by CCR 4–NOT.