J
Jonathan Hyam
Researcher at University College London
Publications - 58
Citations - 1872
Jonathan Hyam is an academic researcher from University College London. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 19, co-authored 56 publications receiving 1420 citations. Previous affiliations of Jonathan Hyam include University of Kent & Aarhus University.
Papers
More filters
Journal ArticleDOI
Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease.
Harith Akram,Stamatios N. Sotiropoulos,Stamatios N. Sotiropoulos,Saâd Jbabdi,Dejan Georgiev,P Mahlknecht,Jonathan Hyam,Thomas Foltynie,Patricia Limousin,Enrico De Vita,Enrico De Vita,Marjan Jahanshahi,Marwan Hariz,Marwan Hariz,John Ashburner,Timothy E.J. Behrens,Timothy E.J. Behrens,Ludvic Zrinzo +17 more
TL;DR: These findings support the presence of overlapping stimulation sites within the subthalamic nucleus and its superior border, with different cortical connectivity patterns, associated with maximum improvement in tremor, rigidity and bradykinesia.
Journal ArticleDOI
Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting
Simon Little,Elina Tripoliti,Martijn Beudel,Alek Pogosyan,Hayriye Cagnan,Damian M. Herz,Sven Bestmann,Tipu Z. Aziz,Binith Cheeran,Ludvic Zrinzo,Marwan Hariz,Jonathan Hyam,Patricia Limousin,Thomas Foltynie,Peter Brown +14 more
TL;DR: It is hypothesised that acute aDBS would be more effective and more efficient than cDBS at matched stimulation parameters while causing less speech impairment, and tested bilateral stimulation, optimising parameters for a DBS, and evaluate speech intelligibility.
Journal ArticleDOI
Bilateral globus pallidus stimulation for severe Tourette's syndrome: a double-blind, randomised crossover trial.
Zinovia Kefalopoulou,Ludvic Zrinzo,Marjan Jahanshahi,Joseph Candelario,Catherine Milabo,Mazda Beigi,Harith Akram,Jonathan Hyam,Jennifer Clayton,Lewis Kass-Iliyya,Monty Silverdale,Julian Evans,Patricia Limousin,Marwan Hariz,Eileen M. Joyce,Thomas Foltynie +15 more
TL;DR: GPi stimulation led to a significant improvement in tic severity, with an overall acceptable safety profile, in patients with severe Tourette's syndrome in a randomised, double-blind, crossover trial.
Journal ArticleDOI
Connectivity derived thalamic segmentation in deep brain stimulation for tremor
Harith Akram,Viswas Dayal,Philipp Mahlknecht,Philipp Mahlknecht,Dejan Georgiev,Jonathan Hyam,Thomas Foltynie,Patricia Limousin,Enrico De Vita,Enrico De Vita,Marjan Jahanshahi,John Ashburner,Timothy E.J. Behrens,Timothy E.J. Behrens,Marwan Hariz,Marwan Hariz,Ludvic Zrinzo +16 more
TL;DR: It is concluded that probabilistic tractography techniques can be used to segment the VL and VP thalamus based on cortical and cerebellar connectivity in patients that will undergo thalamic DBS for tremor.
Journal ArticleDOI
Comparison of P‐POSSUM risk‐adjusted mortality rates after surgery between patients in the USA and the UK
Elliott Bennett-Guerrero,Jonathan Hyam,Shahzad Shaefi,David Prytherch,G. L. Sutton,P. C. Weaver,Monty G. Mythen,Michael P.W. Grocott,Michael K. Parides +8 more
TL;DR: The aim was to determine how applicable Physiological and Operative Severity Score criteria are to patients undergoing surgery in the USA.