J
Jonathan Visentin
Researcher at Centre national de la recherche scientifique
Publications - 160
Citations - 1547
Jonathan Visentin is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Typing & Human leukocyte antigen. The author has an hindex of 16, co-authored 123 publications receiving 1134 citations. Previous affiliations of Jonathan Visentin include University of Bordeaux.
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Journal ArticleDOI
Detection of C3d-Binding Donor-Specific Anti-HLA Antibodies at Diagnosis of Humoral Rejection Predicts Renal Graft Loss
Antoine Sicard,Antoine Sicard,Stéphanie Ducreux,Maud Rabeyrin,Lionel Couzi,Brigitte McGregor,Lionel Badet,Jean-Yves Scoazec,Thomas Bachelet,Sébastien Lepreux,Jonathan Visentin,Pierre Merville,Véronique Frémeaux-Bacchi,Emmanuel Morelon,Emmanuel Morelon,Jean-Luc Taupin,Valérie Dubois,Olivier Thaunat,Olivier Thaunat +18 more
TL;DR: It is concluded that assessment of the C3d-binding capacity of DSA at the time of AMR diagnosis allows for identification of patients at risk for allograft loss.
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Non-Complement–Binding De Novo Donor-Specific Anti-HLA Antibodies and Kidney Allograft Survival
Gwendaline Guidicelli,Florent Guerville,Sébastien Lepreux,Chris Wiebe,Olivier Thaunat,Olivier Thaunat,Valérie Dubois,Jonathan Visentin,Thomas Bachelet,Emmanuel Morelon,Emmanuel Morelon,Peter Nickerson,Pierre Merville,Jean-Luc Taupin,Lionel Couzi +14 more
TL;DR: C1q-binding de novo DSA are associated with graft loss occurring quickly after their appearance and their long-term persistence could lead to lower graft survival.
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Evaluation of the AllType kit for HLA typing using the Ion Torrent S5 XL platform
Marine Cargou,Mamy Ralazamahaleo,Laura Blouin,Isabelle Top,Vincent Elsermans,Marco Andreani,Gwendaline Guidicelli,Jonathan Visentin +7 more
TL;DR: The AllType kit used with the Ion S5 XL platform displayed satisfactory performance for HLA typing in current clinical practice, and was evaluated at evaluating the performance of the One Lambda All type kit using Thermo Fisher Scientific reagents on the ion S5XL platform.
Journal ArticleDOI
Deciphering complement interference in anti-human leukocyte antigen antibody detection with flow beads assays.
Jonathan Visentin,Margaux Vigata,Sophie Daburon,Cécile Contin-Bordes,Véronique Frémeaux-Bacchi,Claire Dromer,Marc-Alain Billes,Martine Neau-Cransac,Gwendaline Guidicelli,Jean-Luc Taupin +9 more
TL;DR: Binding of C4 and C3 activation products is the main responsible for complement interference in flow beads assays, and a complete quenching requires complement activation through C3 cleavage and its amplification by the alternative pathway.
Journal ArticleDOI
Denatured class I human leukocyte antigen antibodies in sensitized kidney recipients: prevalence, relevance, and impact on organ allocation.
Jonathan Visentin,Gwendaline Guidicelli,Thomas Bachelet,Christian Jacquelinet,Benoît Audry,Thoa Nong,Valérie Dubois,Jean-François Moreau,Jar-How Lee,Lionel Couzi,Pierre Merville,Jean-Luc Taupin +11 more
TL;DR: Denatured class I HLA antibodies are common, but the antigens they target should not be considered as unacceptable in most cases, because they negatively impact access to a transplant while predominantly providing negative sensitive crossmatches.