Jordan T. Chang

TL;DR: Although all sealants withstood supraphysiologic arterial pressure, there were differences in characteristics that may be important in clinical outcome.

TL;DR: The data indicate pro-remodelling and the promotion of an anti-inflammatory environment for all injected hydrogels with evidence of full integration with healthy tissue after 28 days, indicating full integration.

TL;DR: In this paper, the authors used a subcutaneous rat model to compare the tissue response, including macrophage phenotype, remodeling potential, and calcification propensity of a biologic scaffold composed of glutaraldehyde-fixed bovine pericardium (GF-BP), the standard of care for heart valve replacement, with those of an electrospun polycarbonate-based supramolecular polymer scaffold (ePC-UPy), urinary bladder extracellular matrix (UBM-ECM), and a polypropylene mesh (PP).

TL;DR: In this article , the pre-clinical safety profile of MBV through a combination of in vitro cytotoxicity and MBV uptake studies and in vivo toxicity, immunotoxicity, and imaging studies was thoroughly characterized.

TL;DR: The results demonstrate the suppressive effects of ECM on glioma and warrant further study.