K
Kirk C. Hansen
Researcher at Anschutz Medical Campus
Publications - 401
Citations - 19006
Kirk C. Hansen is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Medicine & Solar wind. The author has an hindex of 67, co-authored 349 publications receiving 15216 citations. Previous affiliations of Kirk C. Hansen include University of Colorado Hospital & University of California, San Francisco.
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Journal ArticleDOI
CBP/p300-mediated acetylation of histone H3 on lysine 56.
TL;DR: It is shown that, in response to DNA damage, histones bearing acetylated K56 are assembled into chromatin in Drosophila and human cells, forming foci that colocalize with sites of DNA repair.
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67P/Churyumov-Gerasimenko, a Jupiter family comet with a high D/H ratio
Kathrin Altwegg,Hans Balsiger,Akiva Bar-Nun,Jean-Jacques Berthelier,André Bieler,André Bieler,Peter Bochsler,Christelle Briois,Ursina Calmonte,Michael R. Combi,J. De Keyser,Peter Eberhardt,B. Fiethe,Stephen A. Fuselier,Sébastien Gasc,Tamas I. Gombosi,Kirk C. Hansen,Myrtha Hässig,Myrtha Hässig,Annette Jäckel,E. Kopp,A. Korth,Lena Leroy,Ulrich Mall,Bernard Marty,Olivier Mousis,Eddy Neefs,T. C. Owen,Henri Rème,Henri Rème,Martin Rubin,Thierry Sémon,Chia-Yu Tzou,H. Waite,Peter Wurz +34 more
TL;DR: The direct in situ measurement of the D/H ratio in the Jupiter family comet 67P/Churyumov-Gerasimenko by the ROSINA mass spectrometer aboard the European Space Agency's Rosetta spacecraft is found to be (5.3 ± 0.7) × 10−4—that is, approximately three times the terrestrial value.
Journal ArticleDOI
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Hanane Laklai,Yekaterina A. Miroshnikova,Michael W. Pickup,Eric A. Collisson,Grace E. Kim,Alexander S. Barrett,Ryan C. Hill,Johnathon N. Lakins,David D. Schlaepfer,Janna K. Mouw,Valerie S. LeBleu,Nilotpal Roy,Sergey V. Novitskiy,Julia S. Johansen,Valeria Poli,Raghu Kalluri,Christine A. Iacobuzio-Donahue,Laura D. Wood,Matthias Hebrok,Kirk C. Hansen,Harold L. Moses,Valerie M. Weaver +21 more
TL;DR: The findings implicate epithelial tension and matricellular fibrosis in the aggressiveness of SMAD4 mutant pancreatic tumors and highlight STAT3 and mechanics as key drivers of this phenotype.
Journal ArticleDOI
CBP/p300-mediated acetylation of histone H3 on lysine 56 (Nature (2009) 459, (113-117))
TL;DR: This corrects the article to show that the Higgs boson bacterium is a prokaryotic substance, not a “spatially aggregating substance” as previously reported, which can be a source of disease in animals.
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Structural Insights into Histone Demethylation by JMJD2 Family Members
Zhongzhou Chen,Jianye Zang,Johnathan R. Whetstine,Xia Hong,Foteini Davrazou,Tatiana G. Kutateladze,Michael Simpson,Qilong Mao,Cheol-Ho Pan,Shaodong Dai,James Hagman,Kirk C. Hansen,Yang Shi,Gongyi Zhang,Gongyi Zhang +14 more
TL;DR: Sited-directed mutagenesis in conjunction with demethylase activity assays allowed us to propose a molecular model for substrate selection by the JMJD2 histone dem methylase family.