Jos W. R. Meijer

TL;DR: Histologic recovery in celiac disease after starting a gluten-free diet takes time and is incomplete or absent in a substantial subgroup of patients (10.1% villous atrophy after 5 years); systematic follow-up of patients with Celiac disease and the malabsorption syndrome and secondary complications is needed.

TL;DR: Both primary tumours and liver metastases can be used for KRAS mutation analysis, and the concordance of test results between primary tumour and corresponding metastases is high.

TL;DR: A significant and replicable association is reported to a common variant located in intron 28 of the gene myosin IXB (MYO9B), which encodes an unconventionalMyosin molecule that has a role in actin remodeling of epithelial enterocytes, which may explain why immunogenic gluten peptides are able to pass through the epithelial barrier.

TL;DR: In this paper, the authors defined the performance of serologic testing and HLA-DQ typing prospectively for detecting celiac disease and compared with a reference standard of abnormal histologic findings and clinical resolution after a gluten free diet.

TL;DR: Early identification of HLA-DQ2 homozygous CD patients may help to recognize CD patients at risk for developing these severe complications, as well as identify patients atrisk for developing enteropathy-associated T-cell lymphomas.