EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

34 and the only effective treatment is liver transplantation. During the 56th Meeting of the American Association for the Study of Liver Diseases, the International Ascites Club held a Focused Study Group (FSG) on HRS for the purpose of reporting the results of an international workshop and to reach a consensus on a new definition, criteria for diagnosis and recommendations on HRS treatment. A similar workshop was held in Chicago in 1994 in which standardised nomenclature and diagnostic criteria for refractory ascites and HRS were established. 5 The introduction of innovative treatments and improvements in our understanding of the pathogenesis of HRS during the previous decade led to an increasing need to undertake a new consensus meeting. This paper reports the scientific rationale behind the new definitions and recommendations.

/pdf/diagnosis-prevention-and-treatment-of-hepatorenal-syndrome-3yyemrihsu.pdf

Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis

Renal failure, a challenging complication of cirrhosis, is one of the most important risk factors for liver transplantation. In recent years, substantial progress has been made toward understanding the pathogenesis and natural history of renal failure in cirrhosis. This review discusses recently identified information about renal failure in cirrhosis and clinical interventions that may assist in the prevention and management of this complication.

/pdf/renal-failure-in-cirrhosis-1cnfpgh4w1.pdf

Renal Failure in Cirrhosis

https://www.journal-of-hepatology.eu/article/S0168-8278(12)00519-3/pdf

Acute-on chronic liver failure

Loss of Response and Requirement of Infliximab Dose Intensification in Crohn's Disease : A Review

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.20766

Circulatory function and hepatorenal syndrome in cirrhosis.

Open-label infliximab therapy in Crohn´s disease: a long-term multicenter study of efficacy, safety and predictors of response

Hepatitis aguda E en Madrid: descripción de 18 casos

Optimized protocol for diagnosis of acute ileitis.

BACKGROUND & AIMS: Suspected acute ileitis (AI) is a poorly defined clinical condition with multiple causes; its diagnostic protocol has not been standardized properly. We performed a prospective evaluation of the incidence and causes of AI to create a standard protocol for diagnosis. METHODS: The definition of AI included abdominal pain, diarrhea, fever, and at least 1 confirmatory imaging method (abdominal computed tomography scan or ultrasound) showing pathologic changes in the terminal ileum that indicated ileal inflammation. We studied all patients with a presumptive diagnosis of AI seen in the Emergency Room at the Ramon y Cajal Hospital in Madrid, from March 2005 to May 2007, according to a preestablished protocol. Sixty-six patients with primary AI were followed up for at least 6 months. RESULTS: An infectious cause was found in 33.3% of cases; the most frequently detected microorganism was Yersinia spp. A gynecologic condition was identified in 9.1% of cases initially diagnosed as AI, representing 13.95% of the cases among female patients. Crohn’s disease was identified in 12.1% of patients. The diagnostic protocol led to negative results in 33.4% of the patients; 6.1% of patients did not complete the study. The initial diagnosis did not change among any of the patients during the follow-up period. CONCLUSIONS: This protocol led to a definitive diagnosis of AI in more than 60% of potential cases. The most common cause was acute infection. About 10% of cases were of gynecologic origin and about 12% of patients presented with Crohn’s disease.

https://www.cghjournal.org/article/S1542-3565(09)00670-3/pdf

José María Milicua

Papers

Circulatory function and hepatorenal syndrome in cirrhosis.

Open-label infliximab therapy in Crohn´s disease: a long-term multicenter study of efficacy, safety and predictors of response

Hepatitis aguda E en Madrid: descripción de 18 casos

Optimized protocol for diagnosis of acute ileitis.

ORIGINAL ARTICLES—ALIMENTARY TRACT Optimized Protocol for Diagnosis of Acute Ileitis