J
Joseph Leung
Researcher at University of California, Davis
Publications - 416
Citations - 13218
Joseph Leung is an academic researcher from University of California, Davis. The author has contributed to research in topics: Colonoscopy & Biliary tract. The author has an hindex of 60, co-authored 407 publications receiving 12292 citations. Previous affiliations of Joseph Leung include University of Texas Southwestern Medical Center & University of California, Los Angeles.
Papers
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Journal ArticleDOI
Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy
Miao Lin,Wai Han Yiu,Haojia Wu,Loretta Y.Y. Chan,Joseph Leung,WS Au,Kwok Wah Chan,Kar Neng Lai,Sydney C.W. Tang +8 more
TL;DR: Exposure to streptozotocin-induced diabetic and uninephrectomized TLR4-deficient mice had significantly less albuminuria, renal dysfunction, renal cortical NF-κB activation, tubular CCL-2 expression, and interstitial macrophage infiltration than wild-type animals.
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Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: a randomized controlled trial.
Bryan T. Green,Don C. Rockey,Don C. Rockey,G Portwood,Paul R. Tarnasky,Steve Guarisco,Malcolm S. Branch,Joseph Leung,Paul S. Jowell +8 more
TL;DR: Although urgent Colonoscopy identified a definite source of LGIB more often than a standard care algorithm based on angiography and expectant colonoscopy, the approaches are not significantly different with regard to important outcomes.
Journal ArticleDOI
Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo
Sydney C.W. Tang,Joseph Leung,Katsushige Abe,Kwok Wah Chan,Loretta Y.Y. Chan,Tak Mao Chan,Kar Neng Lai +6 more
TL;DR: In conclusion, albumin is a strong stimulus for tubular IL-8 expression, which occurs via NF-kappaB-dependent pathways through PKC activation and ROS generation.
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Endoscopy-based triage significantly reduces hospitalization rates and costs of treating upper GI bleeding: a randomized controlled trial.
John G. Lee,Samuel D. Turnipseed,Patrick S Romano,H. Vigil,Rahman Azari,Norman Melnikoff,R. K. Hsu,Douglas J. Kirk,Peter E. Sokolove,Joseph Leung +9 more
TL;DR: Early endoscopy performed shortly after admission in the emergency department safely triaged 46% of patients with nonvariceal upper GI bleeding to outpatient care, which significantly reduced hospital stay and costs.
Journal ArticleDOI
Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial
TL;DR: Injection of adrenaline is effective in stopping bleeding from actively bleeding ulcers in endoscopy patients admitted for upper gastrointestinal haemorrhage.