J
Joseph S. M. Peiris
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 237
Citations - 33382
Joseph S. M. Peiris is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Influenza A virus & Influenza A virus subtype H5N1. The author has an hindex of 81, co-authored 228 publications receiving 30346 citations. Previous affiliations of Joseph S. M. Peiris include University of Hong Kong & World Health Organization.
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Journal ArticleDOI
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.
Joseph S. M. Peiris,Chung-Ming Chu,V. C. C. Cheng,Kin Sang Chan,Ivan Hung,Leo L.M. Poon,K I Law,Bone S.F. Tang,T Y W Hon,CS Chan,Kwok-ning Chan,J S C Ng,Bo-Jian Zheng,Wing-Chun Ng,Raymond Lai,Yi Guan,Kwok-Yung Yuen +16 more
TL;DR: The consistent clinical progression, shifting radiological infiltrates, and an inverted V viral-load profile suggest that worsening in week 2 is unrelated to uncontrolled viral replication but may be related to immunopathological damage.
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The severe acute respiratory syndrome.
TL;DR: The concerted and coordinated response that contained SARS is a triumph for global public health and provides a new paradigm for the detection and control of future emerging infectious disease threats.
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Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
Yi Guan,Bo-Jian Zheng,Yuxian He,X. L. Liu,Z. X. Zhuang,CL Cheung,S. W. Luo,Philip H. Li,L. J. Zhang,Y. J. Guan,K. M. Butt,K. L. Wong,K. W. Chan,Wilina Lim,Kennedy F. Shortridge,K. Y. Yuen,Joseph S. M. Peiris,Leo L.M. Poon +17 more
TL;DR: The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
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Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings.
Chung-Ming Chu,V C C Cheng,Ivan Hung,M M L Wong,K H Chan,K S Chan,Richard Y.T. Kao,Leo L.M. Poon,C L P Wong,Yi Guan,Joseph S. M. Peiris,Kwok-Yung Yuen +11 more
TL;DR: The apparent favourable clinical response with lopinavir/ritonavir and ribavirin supports further randomised placebo controlled trials in patients with SARS and shows that age, hepatitis B carrier status, and lack of treatment with this antiviral combination were independent predictors of an adverse outcome.
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Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003
Nanshan Zhong,Bo-Jian Zheng,Yimin Li,Leo L.M. Poon,Z. H. Xie,KH Chan,Philip H. Li,S. Y. Tan,Qingsong Chang,J. P. Xie,X. Q. Liu,J. Xu,D. X. Li,Kwok-Yung Yuen,Joseph S. M. Peiris,Yi Guan +15 more
TL;DR: Genetic analysis showed that the SARS CoV isolates from Guangzhou shared the same origin with those in other countries, and had a phylogenetic pathway that matched the spread of SARS to the other parts of the world.