Joseph S. Verducci

TL;DR: A substantial role for microRNAs in anticancer drug response is supported, suggesting novel potential approaches to the improvement of chemotherapy and comparing drug potencies with microRNA expression profiles across the entire NCI-60 panel.

TL;DR: To test whether assaying concomitant block of multiple ion channels (Multiple Ion Channel Effects or MICE) improves predictivity, automated gigaseal patch clamp instruments were used to provide higher throughput along with accuracy and reproducibility and logistic regression models showed a significant reduction in false positives and false negatives.

TL;DR: Measureting expression levels of microRNAs in the NCI-60 and incorporating the resulting data into the CellMiner program package for integrative analysis found that there does not seem to be a significant correlation between microRNA expression patterns and those of known target transcripts.

TL;DR: In this article, a sample of people independently examines a fixed set of k items and then ranks these items according to personal judgment The process of ranking the items is decomposed into k − 1 stages in the forward model, and the best of the remaining items is selected at the second stage, and so on until the least preferred item is selected by default.

TL;DR: In this paper, the authors investigate several probability models on permutations that have been proposed in the statistical and psychological literature and classify them into the following general classes: (1) Thurstone order statistics models, (2) ranking models induced by paired comparisons, (3) ranking based on distances between permutations, and (4) multistage ranking models.