J
Judith A. Woodfolk
Researcher at University of Virginia
Publications - 138
Citations - 6198
Judith A. Woodfolk is an academic researcher from University of Virginia. The author has contributed to research in topics: Immunoglobulin E & Asthma. The author has an hindex of 43, co-authored 128 publications receiving 5502 citations. Previous affiliations of Judith A. Woodfolk include University of Virginia Health System.
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Journal ArticleDOI
Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study.
Thomas A.E. Platts-Mills,John W. Vaughan,Susan Pollart Squillace,Judith A. Woodfolk,Richard Sporik +4 more
TL;DR: Exposure to cat allergen can produce an IgG and IgG4 antibody response without sensitisation or risk of asthma, and this modified T-helper-2 cell response should be regarded as a form of tolerance and may be the correct objective of immunotherapy.
Journal ArticleDOI
Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-α-1,3-galactose.
Scott P. Commins,S.M. Satinover,Jacob D. Hosen,J. Mozena,Larry Borish,Barrett D. Lewis,Judith A. Woodfolk,Thomas A.E. Platts-Mills +7 more
TL;DR: A novel and severe food allergy related to IgE antibodies to the carbohydrate epitope alpha-gal is reported from patients who experience delayed symptoms of anaphylaxis, angioedema, or urticaria associated with eating beef, pork, or lamb.
Journal ArticleDOI
Modulation of the sigma-1 receptor–IRE1 pathway is beneficial in preclinical models of inflammation and sepsis
Dorian A. Rosen,Scott M. Seki,Anthony Fernandez-Castaneda,Rebecca M. Beiter,Jacob D. Eccles,Judith A. Woodfolk,Alban Gaultier +6 more
TL;DR: The contribution of S1R to the restraint of the inflammatory response is revealed and this work identifies sigma-1 receptor (S1R) as an essential inhibitor of cytokine production in a preclinical model of septic shock.
Journal ArticleDOI
Is the hygiene hypothesis still a viable explanation for the increased prevalence of asthma
TL;DR: The hygiene hypothesis states that a reduced exposure to allergens in early life is solely implicated in the growing propensity for allergy sensitization, and lifestyle changes related to obesity (e.g. a change in diet) are associated with asthma.
Journal ArticleDOI
Allergy and Dermatophytes
TL;DR: Characterizing the immunologic properties of Trichophyton allergens and defining immune mechanisms which drive dichotomous responses are pivotal to understanding the dermatophyte-allergy relationship.