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Showing papers by "Jukka S. Jurvelin published in 1997"


Journal ArticleDOI
TL;DR: An optical method for the visualization of boundaries of cylindrical bovine humeral head articular cartilage disks, immersed in physiological solution, and compressed in unconfined geometry revealed that the lateral expansion, especially during the initial phase of relaxation, was inhomogeneous through the tissue depth.

355 citations


Journal ArticleDOI
TL;DR: The non-linear cartilage response to release and sinusoidal displacements therefore appear to be physiologically interesting and compressive stress observed during release may be a beneficial adaptation to repeated loading where temporal variations in tissue stresses would be minimized.

73 citations


01 Jan 1997
TL;DR: In humans most epidemiological studies have failed to prove the connection between running training and cartilage degeneration, but there is evidence that sports activities exposing joints to impact loading might increase the risk of osteoarthrosis.
Abstract: Articular cartilage provides nearly frictionless surfaces for joint movemants and reduces contact pressures, protecting the underlying suchondral bone from excess stress. The unique properties of articular cartilage are based on the interaction of the main components of the extracellular matrix: proteoglycans (PGs), collagen and interstitial fluid. Animal experiments and in vitro studies demonstrate that one of the most important regulators of the extracellular matrix metabolism is mechanical loading acting on the joints. Unloading and immobilization leads to PG depletion and softening of articular cartilage, increasing the risk of permanent cartilage degeneration. Moderate running exercise and increased weight bearing increases cartilage thickness, PG concentration and improves biomechanical properties of articular cartilage. With further increase in training intensity this positive influence of exercise disappears and cartilage shows changes analogous to immobilization of the joint, i.e. PG depletion and softening of the tissue. In humans most epidemiological studies have failed to prove the connection between running training and cartilage degeneration, but there is evidence that sports activities exposing joints to impact loading might increase the risk of osteoarthrosis.

7 citations