J
Julia L. Cook
Researcher at University Medical Center New Orleans
Publications - 31
Citations - 3549
Julia L. Cook is an academic researcher from University Medical Center New Orleans. The author has contributed to research in topics: Angiotensin II & Intracrine. The author has an hindex of 20, co-authored 31 publications receiving 3397 citations.
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Journal ArticleDOI
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.
TL;DR: Results implicate Nrf2 in the induction of the HO-1 gene but suggest that the NRF2 partner in this function is a factor other than p18 or Jun proteins.
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Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury
TL;DR: It is demonstrated for the first time that HO-1 can provide protection against hyperoxia-induced lung injury in vivo by modulation of neutrophil inflammation and lung apoptosis and the feasibility of high-levelHO-1 expression in the rat lung by gene delivery is suggested.
Journal ArticleDOI
Reporter genes: application to the study of mammalian gene transcription.
Jawed Alam,Julia L. Cook +1 more
Journal ArticleDOI
How Many Transcription Factors Does It Take to Turn On the Heme Oxygenase-1 Gene?
Jawed Alam,Julia L. Cook +1 more
TL;DR: Hmox1 is unique in that it is proposed to be directly regulated by all four of these stress-responsive transcription factors, and analysis of the data supporting this proposition is provided.
Journal ArticleDOI
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide
TL;DR: It is demonstrated that the NO donor spermine NONOate (SNN) increases steady-state levels of HO-1 mRNA in aortic vascular smooth muscle cells (aSMC) in both a time- and dose-dependent manner, providing evidence for an important regulatory network between NO and CO viaHO-1.