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Julia Y. Wang

Researcher at Brigham and Women's Hospital

Publications -  38
Citations -  1419

Julia Y. Wang is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 16, co-authored 34 publications receiving 1218 citations. Previous affiliations of Julia Y. Wang include Memorial Sloan Kettering Cancer Center.

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A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization.

TL;DR: The results are the basis for the discovery of small-molecule inhibitors of the protein-protein interaction between human calcineurin and NFAT transcription factors, as discussed in the subsequent paper.
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Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides

TL;DR: The results provide a structure/function rationale for abscess formation by S. aureus and expand the sphere of encapsulated organisms that interact directly with T cells to regulate this host response to bacterial infection.
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A dually active anthrax vaccine that confers protection against both bacilli and toxins.

TL;DR: DAAV combines both antibacterial and antitoxic components in a single vaccine against anthrax, introducing a vaccine design that may be widely applicable against infectious diseases and provides additional tools in medicine and biodefense.
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Glycosaminoglycans are a potential cause of rheumatoid arthritis

TL;DR: It is shown that injection of GAGs such as hyaluronic acid, heparin, and chondroitin sulfates A, B, and C induce arthritis, tendosynovitis, dermatitis, and other pathological conditions in mice and suggests that carbohydrate self-antigenic G AGs provoke autoimmune dysfunctions that involve the expansion of G AG-binding cells which migrate to anatomical sites rich in GAGS.
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Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer.

TL;DR: Hparin affinity fractionation enrichment (HAFE) is described as a prefractionation tool for the study of the human primary tissue proteome and the discovery of PSB7, PRDX1, and SRP9 up-regulation as candidate biomarkers of colon cancer.