J
Julian C. Rutherford
Researcher at Newcastle University
Publications - 26
Citations - 3512
Julian C. Rutherford is an academic researcher from Newcastle University. The author has contributed to research in topics: Saccharomyces cerevisiae & Cryptococcus neoformans. The author has an hindex of 20, co-authored 25 publications receiving 3182 citations. Previous affiliations of Julian C. Rutherford include University of Utah & University of Newcastle.
Papers
More filters
Journal ArticleDOI
Metalloproteins and metal sensing
TL;DR: Almost half of all enzymes must associate with a particular metal to function, and for metalloproteins to acquire the right metals, metal sensors must correctly distinguish between the inorganic elements.
Journal ArticleDOI
Sensing the environment: lessons from fungi
Yong Sun Bahn,Chaoyang Xue,Alexander Idnurm,Julian C. Rutherford,Joseph Heitman,Maria E. Cardenas +5 more
TL;DR: Recent progress is reviewed in understanding of how fungal-signalling circuits operate at the molecular level to sense and respond to a plethora of environmental cues.
Journal ArticleDOI
Metal-Responsive Transcription Factors That Regulate Iron, Zinc, and Copper Homeostasis in Eukaryotic Cells
TL;DR: The ability to mediate metal-responsive gene expression is an important aspect of metal homeostasis in those organisms that contain these factors.
Journal ArticleDOI
Role of glutaredoxin-3 and glutaredoxin-4 in the iron-regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae
TL;DR: It is shown that the nuclear monothiol glutaredoxins Grx3 and Grx4 are critical for iron inhibition of Aft1 in yeast cells and are novel components required for AFT1 iron regulation that most likely occurs in the nucleus.
Journal ArticleDOI
Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis
TL;DR: Iron sensing by Aft1/Aft2 is not linked to the maturation of cytosolic/nuclear Fe-S proteins, but the mitochondrial inner membrane transporter Atm1 is important to transport the inhibitory signal.