Julianne Byrne

TL;DR: It is demonstrated that fertility is decreased among female Childhood Cancer Survivor Study participants, and the risk factors identified may be utilized for pretreatment counseling of patients and their parents.

TL;DR: Cox regression analysis showed that cancer survivors who married and were presumed to be at risk of pregnancy were less likely than their sibling controls to have ever begun a pregnancy.

TL;DR: The present study provides reassurance that cancer treatment using older protocols does not carry a large risk for genetic disease in offspring conceived many years after treatment, and cannot rule out the possibility that new therapeutic agents or specific combinations of agents at high doses may damage germ cells.

TL;DR: Clinical reports of small numbers of pediatric brain tumor patients observed for brief periods suggest that long-term survivors continue to have major handicaps into adulthood, and clinicians should anticipate late effects, such as those observed, and target subgroups for interventions that may improve subsequent quality of life.

TL;DR: Cox regression analysis showed that cancer survivors who married and were presumed to be at risk of pregnancy were less likely than their sibling controls to have ever begun a pregnancy, and relative fertility in the survivors varied considerably according to sex, site of cancer, and type of treatment.