J
Julianne Meyne
Researcher at Los Alamos National Laboratory
Publications - 28
Citations - 3015
Julianne Meyne is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: DNA & Telomere. The author has an hindex of 18, co-authored 28 publications receiving 2915 citations.
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Conservation of the human telomere sequence (TTAGGG)n among vertebrates.
TL;DR: The conservation of the (TTAGGG)n sequence and its telomeric location, in species thought to share a common ancestor over 400 million years ago, strongly suggest that this sequence is the functional vertebrate telomere.
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Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes.
Julianne Meyne,Robert J. Baker,Holly H. Hobart,T. C. Hsu,Oliver A. Ryder,Oscar G. Ward,John E. Wiley,Doris H. Wurster-Hill,Terry L. Yates,Robert K. Moyzis +9 more
TL;DR: Possible relationships between the non-telomeric distribution of the (TTAGGG)n sequence and the process of karyotype evolution, during which these sites may provide potential new telomeres are discussed.
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DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes
Susan M. Bailey,Julianne Meyne,David J. Chen,Akihiro Kurimasa,Gloria C. Li,Bruce E. Lehnert,Edwin H. Goodwin +6 more
TL;DR: These studies demonstrate that DNA double-strand break repair genes play a dual role in maintaining chromosomal stability in mammalian cells, the known role in repairing incidental DNA damage, as well as a new protective role in telomeric end-capping.
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Isolation and molecular characterization of a highly polymorphic centromeric tandem repeat in the family Falconidae.
Jonathan L. Longmire,Annette K. Lewis,Nancy C. Brown,Judith M. Buckingham,Lynn M. Clark,Myrna D. Jones,Linda Meincke,Julianne Meyne,Robert L. Ratliff,F. Andrew Ray,Robert P. Wagner,Robert K. Moyzis +11 more
TL;DR: The cloned merlin repeat reveals highly polymorphic restriction patterns in the peregrine falcon (Falco pere grinus), which can be used to differentiate the Greenland and Argentina populations of this endangered raptor species.
Journal ArticleDOI
Highly conserved repetitive DNA sequences are present at human centromeres.
Deborah L. Grady,Robert L. Ratliff,Donna L. Robinson,Erin C. Mccanlies,Julianne Meyne,Robert K. Moyzis +5 more
TL;DR: The extreme evolutionary conservation of this DNA sequence, its centromeric location, its unusual hydrogen bonding properties, its high affinity for specific nuclear proteins, and its similarity to functional centromeres isolated from yeast suggest that this sequence may be a component of the functional human centromere.