J
Julien Marcoux
Researcher at University of Toulouse
Publications - 68
Citations - 2393
Julien Marcoux is an academic researcher from University of Toulouse. The author has contributed to research in topics: Chemistry & Membrane protein. The author has an hindex of 22, co-authored 56 publications receiving 1866 citations. Previous affiliations of Julien Marcoux include University of Oxford & University of Grenoble.
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Journal ArticleDOI
Structure of the TatC core of the twin-arginine protein transport system
Sarah E. Rollauer,Michael Tarry,Michael Tarry,James E. Graham,James E. Graham,Mari Jääskeläinen,Franziska Jäger,Steven Johnson,Martin Krehenbrink,Sai Man Liu,Michael J. Lukey,Michael J. Lukey,Julien Marcoux,Melanie A. Mcdowell,Fernanda Rodriguez,Pietro Roversi,Pietro Roversi,Phillip J. Stansfeld,Carol V. Robinson,Mark S.P. Sansom,Tracy Palmer,Martin Högbom,Ben C. Berks,Susan M. Lea +23 more
TL;DR: The crystal structure of TatC from the hyperthermophilic bacterium Aquifex aeolicus is reported, providing a molecular description of the core of the Tat translocation system and a framework for understanding the unique Tat transport mechanism.
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Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane.
Laura Chiaradia,Cyril Lefebvre,Julien Parra,Julien Marcoux,Odile Burlet-Schiltz,Gilles Etienne,Maryelle Tropis,Mamadou Daffé +7 more
TL;DR: The plasma membranes and the native MM-containing cell walls of two rapid-growing mycobacterial species, Mycobacterium aurum and M. smegmatis, were isolated from their cell lysates by differential ultracentrifugation and biochemical analyses demonstrated that the two membranes were virtually pure.
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Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump
Julien Marcoux,Sheila C. Wang,Argyris Politis,Eamonn Reading,Jerome Ma,Philip C. Biggin,Min Zhou,Houchao Tao,Qinghai Zhang,Geoffrey Chang,Nina Morgner,Carol V. Robinson +11 more
TL;DR: Overall these MS results show how concerted small molecule binding leads to synergistic effects on binding affinities and conformations of a multidrug efflux pump.
Journal ArticleDOI
Twenty Years of Gas Phase Structural Biology
Julien Marcoux,Carol V. Robinson +1 more
TL;DR: Recent progress in the study of protein complexes is considered, focusing particularly on complexes extracted from membranes, and future prospects for gas phase structural biology are outlined.
Journal ArticleDOI
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Sung Chang Lee,Brad C. Bennett,Wen-Xu Hong,Yu Fu,Kent A. Baker,Julien Marcoux,Carol V. Robinson,Andrew B. Ward,James R. Halpert,Raymond C. Stevens,C.D. Stout,Mark Yeager,Mark Yeager,Qinghai Zhang +13 more
TL;DR: In this article, a family of steroid-based facial amphiphiles (FAs) was developed to stabilize MPs and form relatively small protein-detergent complexes (PDCs), a property considered favorable for MP crystallization.