J
Jun-ichi Iga
Researcher at Ehime University
Publications - 119
Citations - 2437
Jun-ichi Iga is an academic researcher from Ehime University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 88 publications receiving 1914 citations. Previous affiliations of Jun-ichi Iga include University of Tokushima.
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Journal ArticleDOI
GABA concentration in schizophrenia patients and the effects of antipsychotic medication: A proton magnetic resonance spectroscopy study
Shin'Ya Tayoshi,Masahito Nakataki,Satsuki Sumitani,Kyoko Taniguchi,Sumiko Shibuya-Tayoshi,Shusuke Numata,Jun-ichi Iga,Shu-ichi Ueno,Masafumi Harada,Tetsuro Ohmori +9 more
TL;DR: There are no differences in GABA concentrations in the anterior cingulate cortex or the left basal ganglia of schizophrenia patients compared to healthy controls, and this is the first study to have directly measured GABA concentration in schizophrenia patients using (1)H-MRS.
Journal ArticleDOI
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms.
Shusuke Numata,Shu-ichi Ueno,Jun-ichi Iga,Ken Yamauchi,Song Hongwei,Koji Ohta,Sawako Kinouchi,Sumiko Shibuya-Tayoshi,Shin'Ya Tayoshi,Michitaka Aono,Naomi Kameoka,Satsuki Sumitani,Masahito Tomotake,Yasuhiro Kaneda,Takahide Taniguchi,Yasuhito Ishimoto,Tetsuro Ohmori +16 more
TL;DR: The investigation indicates that the BDNF gene Val66Met polymorphism is related to the onset age of schizophrenia and the levels of clinical symptoms that remain after long-term antipsychotic treatment.
Journal ArticleDOI
Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS).
Shin'Ya Tayoshi,Satsuki Sumitani,Kyoko Taniguchi,Sumiko Shibuya-Tayoshi,Shusuke Numata,Jun-ichi Iga,Masahito Nakataki,Shu-ichi Ueno,Shu-ichi Ueno,Masafumi Harada,Tetsuro Ohmori +10 more
TL;DR: Investigation of changes in metabolites in the anterior cingulate cortex and left basal ganglia of patients with chronic schizophrenia using proton magnetic resonance spectroscopy suggested an involvement of mI in the pathophysiology of schizophrenia.
Journal ArticleDOI
Gene expression and association analysis of vascular endothelial growth factor in major depressive disorder.
Jun-ichi Iga,Shu-ichi Ueno,Ken Yamauchi,Shusuke Numata,Surniko Tayoshi-Shibuya,Sawako Kinouchi,Masahito Nakataki,Hongwei Song,Kazuhiko Hokoishi,Hirotaka Tanabe,Akira Sano,Tetsuro Ohmori +11 more
TL;DR: The investigation indicates that the higher expression levels of VEGF mRNA in the peripheral leukocytes are associated with the depressive state and their recovery after treatment may beassociated with the clinical improvement.
Journal ArticleDOI
The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with psychotic feature and suicidal behavior in Japanese major depressive patients†
Jun-ichi Iga,Shu-ichi Ueno,Ken Yamauchi,Shusuke Numata,Sumiko Tayoshi-Shibuya,Sawako Kinouchi,Masahito Nakataki,Hongwei Song,Kazuhiko Hokoishi,Hirotaka Tanabe,Akira Sano,Tetsuro Ohmori +11 more
TL;DR: The results suggest that the BDNF Val66Met polymorphism is not related to the development of MDD but related to clinical features ofMDD in a Japanese population.