Jun Li

TL;DR: Treatment concept for CHD is provided by balancing the switch between the two responses of apoptosis and autophagy and some therapeutic drugs and pharmacologic compounds involving mTOR inhibitor and AMPK activator have been reported to regulate apoptosis.

TL;DR: Patients with a previous myocardial infarction and chronic heart failure could potentially benefit from isolated CABG combined with autologous BMMNCs delivered through a graft vessel.

TL;DR: It is demonstrated that treatment of CFs with pirfenidone resulted in decreased proliferation, and attenuated fibroblast α-smooth muscle actin expression and collagen contractility, and point to its potential use in the treatment of adverse myocardial remodeling.

TL;DR: It is found that the proliferation level and cell cycle-associated genes in MSCs were increased after LLLI treatment in a time-dependent manner, and miR-193 was the most highly up-regulated miRNA, and the change in it was related with the proliferationlevel.

TL;DR: BMSCs from older patients with heart valve diseases could be harvested and expanded successfully, and the phenotype and morphology were uniform as nonaged groups, however, the proliferative and differentiation properties of aged cells, as well as cytokine release and migratory abilities, are significantly impaired.