J
Jun Sub Im
Researcher at Seoul National University
Publications - 2
Citations - 948
Jun Sub Im is an academic researcher from Seoul National University. The author has contributed to research in topics: Senescence & Gene expression. The author has an hindex of 2, co-authored 2 publications receiving 735 citations.
Papers
More filters
Journal ArticleDOI
Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase
Bo Yun Lee,Jung A. Han,Jun Sub Im,Amelia Morrone,Kimberly L. Johung,Edward C. Goodwin,Wim J. Kleijer,Daniel DiMaio,Eun Seong Hwang,Eun Seong Hwang +9 more
TL;DR: It is demonstrated here that SA‐β‐gal activity is expressed from GLB1, the gene encoding lysosomal β‐D‐galactosidase, the activity of which is typically measured at acidic pH 4.5.
Journal ArticleDOI
Induction of senescence-like state and suppression of telomerase activity through inhibition of HPV E6/E7 gene expression in cells immortalized by HPV16 DNA.
Chan Jae Lee,Eun Jung Suh,Hyun Tae Kang,Jun Sub Im,Soo-Jong Um,Jong Sup Park,Eun Seong Hwang +6 more
TL;DR: A senescence program exists in cells immortalized by HPV DNA as well as in cervical carcinoma cells, which suggests that the HPV E6 and E7 proteins are required not only for induction of the proliferative phenotype and telomerase activity, but also for their maintenance.