J
Jun Sun
Researcher at China Medical University (PRC)
Publications - 2
Citations - 157
Jun Sun is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Osteoblast & GPX4. The author has an hindex of 2, co-authored 2 publications receiving 20 citations.
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Journal ArticleDOI
Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis
TL;DR: Melatonin significantly reduced the level of ferroptosis and improved the osteogenic capacity of MC3T3-E1 through activating the Nrf2/HO-1 pathway in vivo and in vitro and confirmed that melatonin can inhibit the ferroPTosis of osteoblasts through activating NRF2/ HO-1 signaling pathway to improve bone microstructure.
Journal ArticleDOI
NIPA2 regulates osteoblast function via its effect on apoptosis pathways in type 2 diabetes osteoporosis.
TL;DR: The study revealed the changes of NIPA2 in response to AGEs in the environment, as well as its function and mechanism in osteoblasts, demonstrating its important role in the pathogenesis of type 2 diabetes osteoporosis.