Jun Zhang

TL;DR: Clear genetic evidence is provided for understanding occurrence time and historical process of polyploidy inPolyploid vertebrates by identifying two divergent Dmrt1 genes and localized the two genes on three homologous chromosomes.

TL;DR: The findings uncover a potential new mechanism in the evolution of sex determination system in polyploid vertebrates with unisexual gynogenesis ability, and reveal a possible association ofsex determination mechanism transition between TSD and GSD and reproduction mode transition between unisexualgynogenesis and bisexual reproduction.

TL;DR: It is demonstrated that unisexual gynogenetic embryos remain keeping male sex determination information in the genome, and the complete depletion of primordial germ cells in the all-female fish leads to sex-biased gene expression alteration and sterile all-male occurrence.

TL;DR: Identification of a fish MAVS orthologue from crucian carp Carassius auratus blastulae embryonic (CAB) cells and its function role in fish RLR signaling are reported and results indicate that fishMAVS contributes to IFN antiviral immunity downstream of cytosolic poly (I:C) and RIG-I and upstream of TBK1 and IRF3/7.

TL;DR: It is reported that grass carp reovirus-induced gene 1 (Gig1) was a typical fish ISG, and Gig1 homologs were found exclusively in fish species forming a novel gene family, illustrating that there exists a Gig1 gene family unique to fish species and the founding gene mediates a novel fish IFN antiviral pathway.