Junchao Kong

TL;DR: Treatment with PRP combined with allogeneic bone marrow mesenchymal stem cells significantly promotes healing of osteoporotic bone defects and expression levels of osteogenesis-specific marker genes including RUNX2, OSX, and OPN were significantly upregulated in rats treated withPRP and BMSCs compared to those of other groups.

TL;DR: It is suggested that mitochondrial Mcl−1 is an essential signaling mediator regulating the activation of autophagy and apoptosis during T. gondii infection.

TL;DR: Aloin promotes osteogenic differentiation of BMSCs through activation of the ERK1/2-Runx2 signaling pathway and effectively attenuated Runx2 activation in these cells and also suppressed osteoblastic differentiation.

TL;DR: In vitro biocompatibility of PLGA scaffold, in terms of bone mesenchymal stem cells attachment, spreading and proliferation was greatly enhanced by nHAP coating and multilayer deposition, which remarkably improved PLGA surface and mechanical properties.

TL;DR: The histological analyses suggested that the composite scaffold substantially promotes its integration in the host tissue accompanied with a low inflammatory reaction and new tissue formation.