Junguo Ma

TL;DR: Toxicity of multiple metal mixtures of Cr, Cd and Pb has antioxidant and immunotoxic effects on C. carpio and cytokine alterations may result in an immune suppression or excessive activation in the treated common carp as well as cause immune dysfunction or reduced immunity.

TL;DR: The biochemical assays results revealed that GLY treatment remarkably altered the transcriptional levels of HSP70 and HSP90; inhibited the activities of SOD, CAT, GPx, GR, and T-AOC; reduced the contents of GSH, but remarkably promoted MDA and PC contents, suggesting thatGLY exposure induced oxidative stress and lipids and proteins damage in the carp gills.

TL;DR: Results suggest that oxidative stress might be involved in CPF toxicity on goldfish, andPolymerase chain reaction results reveal that CPF exposure downregulates CYP 3A transcription in goldfish liver, suggesting that goldfish CYP3A may be not involved inCPF bioactivation.

TL;DR: Investigation of the effects of PQ on traditional serum parameters and circulating microRNAs in common carp found that serum circulating miRNAs were generally promoted in fish following PQ exposure, suggesting that serum ccr‐mir‐122, ccr-mir‐125b, cCr‐Mir‐146a, and ccr•mir‐155 could be new biomarkers of PZ toxicity in fish.

TL;DR: It is hypothesized that the pathogenesis of human hepatitis and hepatocarcinoma caused by MCs might be closely associated with oxidative stress and inflammation.