J
Junxia Wang
Researcher at South China University of Technology
Publications - 25
Citations - 865
Junxia Wang is an academic researcher from South China University of Technology. The author has contributed to research in topics: Nanocarriers & Drug delivery. The author has an hindex of 13, co-authored 21 publications receiving 617 citations. Previous affiliations of Junxia Wang include Hefei University of Technology.
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Journal ArticleDOI
Semiconducting polymer-based nanoparticles with strong absorbance in NIR-II window for in vivo photothermal therapy and photoacoustic imaging.
TL;DR: A thieno-isoindigo derivative-based semiconducting polymer, PBTPBF-BT, formulated into PEGylated nanoparticles exhibited strong absorption in NIR-II region, inherent high photothermal conversion efficacy, and excellent photostability, suggesting the great probability of using NPPBTP BF-BT for in vivo PA imaging-guided PTT in the Nir-II window.
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ROS-Sensitive Polymeric Nanocarriers with Red Light-Activated Size Shrinkage for Remotely Controlled Drug Release
Ziyang Cao,Ziyang Cao,Yinchu Ma,Chun-Yang Sun,Zi-Dong Lu,Zeyu Yao,Junxia Wang,Dongdong Li,Youyong Yuan,Xianzhu Yang +9 more
TL;DR: A reactive oxygen species (ROS)-sensitive polymeric nanocarrier TK-PPE@NPCe6/DOX was explored to realize remotely controlled drug release by light-activated size shrinkage by triggering rapid DOX release.
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The potentiated checkpoint blockade immunotherapy by ROS-responsive nanocarrier-mediated cascade chemo-photodynamic therapy.
Hu Liqin,Ziyang Cao,Leilei Ma,Zhongqiu Liu,Guochao Liao,Junxia Wang,Song Shen,Dongdong Li,Xianzhu Yang +8 more
TL;DR: The use of cascade chemo-photodynamic therapy with reactive oxygen species (ROS)-sensitive lipid-polymer hybrid nanoparticles TKHNP-C/D to potentiate the antitumor efficacy of anti-PD-L1 antibody to generate an abscopal effect which could simultaneously inhibit primary and distant tumor growth.
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NIR‐Activated Supersensitive Drug Release Using Nanoparticles with a Flow Core
TL;DR: Polymeric nanoparticles observed with flowable core can achieve NIR‐activated supersensitive drug release under the assistance of photothermal agent, which significantly enhances its anticancer efficacy, resulting in overcoming of the resistance of cancer cells against DOX treatment in vitro and in vivo.
Journal ArticleDOI
A Donor–Acceptor Conjugated Polymer with Alternating Isoindigo Derivative and Bithiophene Units for Near-Infrared Modulated Cancer Thermo-Chemotherapy
Dongdong Li,Junxia Wang,Yan Ma,Haisheng Qian,Dong Wang,Li Wang,Guobing Zhang,Longzhen Qiu,Yucai Wang,Xianzhu Yang +9 more
TL;DR: In vivo and in vitro experiments demonstrated that PBIBDF-BT@NPPPE exhibits efficient photothermal anticancer efficacy and could simultaneously encapsulate other types of therapeutic agents though hydrophobic interactions with the PHEP core and achieve NIR-triggered intracellular drug release and a synergistic combination therapy of thermo-chemotherapy for the treatment of cancer.