J
Jürg Hamacher
Researcher at Saarland University
Publications - 47
Citations - 1485
Jürg Hamacher is an academic researcher from Saarland University. The author has contributed to research in topics: Lung & Transplantation. The author has an hindex of 20, co-authored 43 publications receiving 1332 citations. Previous affiliations of Jürg Hamacher include University of Konstanz & University of Bern.
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Journal ArticleDOI
Anti-platelet drugs and outcome in severe infection: clinical impact and underlying mechanisms.
Johannes Winning,Julia Reichel,Yvonne Eisenhut,Jürg Hamacher,Matthias Kohl,Hans-Peter Deigner,Ralf A. Claus,Michael Bauer,Wolfgang Lösche +8 more
TL;DR: It is shown that clopidogrel suppressed endotoxin-induced up-regulation of inflammation-relevant genes, including arachidonate-5-lipoxygenase activating protein and leukotriene B4 receptor 1, which could lead to a possible benefit of anti-platelet drugs in patients on risk for systemic inflammation and organ failure.
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Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury
Christian M. Kähler,Jutta Wechselberger,Wolfgang Hilbe,Andreas Gschwendtner,Daniela Colleselli,Harald Niederegger,Eva-Maria Boneberg,Gilbert Spizzo,Albrecht Wendel,Eberhard Gunsilius,Josef R. Patsch,Jürg Hamacher,Jürg Hamacher +12 more
TL;DR: Transplanted EPC may play an important role in reestablishing the endothelial integrity in vessels after severe injury or at inflamatory sites and might further contribute to vascular repair or wound healing processes in severely damaged tissue.
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Pulmonary fibrosis with predominant CD8 lymphocytic alveolitis and anti-Jo-1 antibodies
A Sauty,Thierry Rochat,Otto D. Schoch,Jürg Hamacher,Anne-Marie Kurt,JM Dayer,Laurent P. Nicod +6 more
TL;DR: It is suggested that this form of interstitial lung disease apparently has a poor response to steroids and cytotoxic drugs, but may respond to moderate doses of cyclosporine and azathioprine in addition to low doses of steroids.
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Superior vena cava syndrome in thoracic malignancies.
Philipp M. Lepper,Sebastian Robert Ott,Hanno Hoppe,Christian Schumann,Uz Stammberger,António Bugalho,Steffen Frese,Michael Schmücking,Norbert M. Blumstein,Nicolas Diehm,Robert Bals,Jürg Hamacher +11 more
TL;DR: This review gives an interdisciplinary overview of the pathophysiology, etiology, clinical manifestations, diagnosis, and treatment of malignant SVCS.
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Osteoporosis in patients undergoing lung transplantation.
S. Ferrari,Laurent P. Nicod,Jürg Hamacher,Anastase Spiliopoulos,DO Slosman,Thierry Rochat,J P Bonjour,R Rizzoli +7 more
TL;DR: Evaluation of bone mass and prevention of bone loss should be considered early before lung transplantation, and the efficacy of antiresorptive drugs on the prevention of accelerated bone loss and vertebral fractures after transplantation is needed.