J
Juxiong Liu
Researcher at Jilin University
Publications - 62
Citations - 1523
Juxiong Liu is an academic researcher from Jilin University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 17, co-authored 45 publications receiving 894 citations. Previous affiliations of Juxiong Liu include China Medical University (PRC).
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Journal ArticleDOI
Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model.
Guangxin Chen,Xin Ran,Bai Li,Yuhang Li,Dewei He,Bingxu Huang,Shoupeng Fu,Juxiong Liu,Wei Wang +8 more
TL;DR: It is indicated that SB ameliorated the TNBS-induced inflammatory response and intestinal epithelium barrier dysfunction through activating GPR109A and inhibiting the AKT and NF-κB p65 signaling pathways and provide a new theoretical basis for treatment of IBD.
Journal ArticleDOI
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms
Shoupeng Fu,Jianfa Wang,Wen-Jing Xue,Hong-Mei Liu,Bingrun Liu,Yalong Zeng,Su-Nan Li,Bingxu Huang,Qing-Kang Lv,Wei Wang,Juxiong Liu +10 more
TL;DR: BHBA concentration-dependently attenuated the LPS-induced decrease in [3H]DA uptake and loss of TH-ir neurons in the primary mesencephalic neuron/glia mixed culture and supports the effectiveness of BHBA in protecting dopaminergic neurons against inflammatory challenge.
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BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
Shoupeng Fu,Su-Nan Li,Jianfa Wang,Yang Li,Shan-shan Xie,Wen-Jing Xue,Hong-Mei Liu,Bingxu Huang,Qing-Kang Lv,Liancheng Lei,Guowen Liu,Wei Wang,Juxiong Liu +12 more
TL;DR: The data suggest that BHBA has a potential as neuroprotective drug candidate in neurodegenerative diseases, and GPR109A is essential to this function.
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Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
Bingxu Huang,Juxiong Liu,Tianyu Meng,Yuhang Li,Dewei He,Xin Ran,Guangxin Chen,Guangxin Chen,Wenjin Guo,Xingchi Kan,Shoupeng Fu,Wei Wang,Dianfeng Liu +12 more
TL;DR: Results are the first to demonstrate that PLD prevents dopaminergic neurodegeneration due to microglial activation via regulation of the AKT/GSK3β-Nrf2/NF-κB signaling axis.
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Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes.
Xinwei Li,Hui Chen,Yuan Guan,Xiaobing Li,Liancheng Lei,Juxiong Liu,Liheng Yin,Guowen Liu,Zhe Wang +8 more
TL;DR: Results indicate that acetic acid activates the AMPKα signaling pathway to increase lipid oxidation and decrease lipid synthesis in bovine hepatocytes, thereby reducing liver fat accumulation in dairy cows.