Showing papers by "K. N. Houk published in 1983"
TL;DR: NMR spectra of the free bases and salts of phenyladamantylpiperidine and phenylcyclohexylpipersidine and an X-ray crystal structure of the adamantane derivative verify the preferred conformations of these molecules in solution and the solid state.
Abstract: The barriers to rotation of the aryl groups of m-nitrophenyladamantylpiperidine and m-nitrophenylcyclohexylpiperidine have been studied by variable-temperature NMR spectroscopy. NMR spectra of the free bases and salts of phenyladamantylpiperidine and phenylcyclohexylpiperidine (phencyclidine) and an X-ray crystal structure of the adamantane derivative verify the preferred conformations of these molecules in solution and the solid state. Force-field calculations provide additional information on the energetics of conformational processes in these molecules.
16 citations
TL;DR: The relative acidities of fiteen aldimines and ketimines have been measured in THF using either 13C nmr spectroscopy or trapping experiments with methyl iodide as mentioned in this paper.
Abstract: The relative acidities of fiteen aldimines and ketimines have been measured in THF using either 13C nmr spectroscopy or trapping experiments with methyl iodide. The pKA's are found to vary over a r...
16 citations
14 citations