K
K. Narumi
Researcher at Tohoku University
Publications - 9
Citations - 162
K. Narumi is an academic researcher from Tohoku University. The author has contributed to research in topics: Hepatocyte growth factor & 67 kDa Laminin Receptor. The author has an hindex of 6, co-authored 9 publications receiving 158 citations.
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Journal ArticleDOI
Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice.
Michiyo Saimura,Eishi Nagai,Kazuhiro Mizumoto,Naoki Maehara,Hidenobu Okino,Mitsuo Katano,Kunio Matsumoto,Toshikazu Nakamura,K. Narumi,Toshihiro Nukiwa,Masao Tanaka +10 more
TL;DR: It is indicated that the intraperitoneal transduction of adenovirus-mediated NK4 gene may be a useful therapeutic modality to prevent the development of peritoneal dissemination of pancreatic cancer.
Journal ArticleDOI
Diminution of 37-kDa laminin binding protein expression reduces tumour formation of murine lung cancer cells
Ken Satoh,K. Narumi,Tatsuya Abe,Toshihiko Sakai,Toshiaki Kikuchi,Masashi Tanaka,T Shimo-Oka,M Uchida,F Tezuka,Mamoru Isemura,Toshihiro Nukiwa +10 more
TL;DR: It is suggested that the suppressed expression of 37LBP/p40 reduces the capability of lung cancer cell proliferation in vitro and tumour formation in vivo.
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Gallbladder cancer treatment using adenovirus expressing the HGF/NK4 gene in a peritoneal implantation model
Toshihiro Tanaka,Hideo Shimura,Takamitsu Sasaki,K. Narumi,Makoto Maemondo,Toshihiro Nukiwa,Kunio Matsumoto,Toshikazu Nakamura,Seiyo Ikeda +8 more
TL;DR: Both the invasion and migration of GB-d1 cells were dramatically inhibited by this vector in a multiplicity of infection (MOI)-dependent manner, and the use of NK4 gene transfer could be an effective modality for preventing peritoneal metastasis of gallbladder cancer.
Journal ArticleDOI
Leucine-rich repeat region of decorin binds to filamin-A.
Koji Yoshida,Yasuyuki Suzuki,Eiko Honda,Kana Amemiya,Tatsuya Nakatani,Masahito Ebina,K. Narumi,Ken Satoh,Hiroshi Munakata +8 more
TL;DR: It is reported that the LRR region of decorin interacts with the cytoskeletal protein, filamin-A (ABP-280), a peripheral cytoplasmic protein, and this interaction is dependent on the 288 carboxyl-terminal amino acids of filamin
Journal ArticleDOI
Towards an Effective Gene Therapy for Idiopathic Pulmonary Fibrosis: Anti-inflammation, Antifibrosis, and Regeneration
Masahito Ebina,Minoru Shimizukawa,K. Narumi,Makoto Miki,Daizo Koinuma,Mika Watanabe,Hiroshi Munakata,Toshihiro Nukiwa +7 more
TL;DR: In this paper, gene expression patterns were quite homogenous among pulmonary fibrosis and control samples, despite the expected variability in genetic background and condition of subjects, and they determined that 100 genes were significantly differentially expressed between UIP and control lungs.