Kae Nakamura

TL;DR: It is demonstrated that plasma-activated medium also had an anti-tumor effect on chemo-resistant cells in vitro and in vivo and may contribute to a better patient prognosis in the future.

TL;DR: PAM downregulated the expression of AKT kinase, a marker molecule in a survival signal transduction pathway, which suggests that PAM may be a promising tool for therapy of glioblastoma brain tumors by downregulating the survival signals in cancers.

TL;DR: Flow cytometry and western blot analysis showed that plasma treatment of ovarian cancer cells induced apoptosis, and nonequilibrium atmospheric pressure plasma could be a promising tool for therapy for ovarian cancers.

TL;DR: Non-equilibrium atmospheric pressure plasmas generate a high electron density using Ar gas and selectively induced the apoptotic death of glioblastoma tumor cells, but did not kill normal mammary epithelial cells.

TL;DR: In vitro and in vivo experiments demonstrated that plasma-activated Ringer’s lactate solution has anti-tumor effects, and nuclear magnetic resonance analyses indicate that plasma irradiation generates acetyl and pyruvic acid-like groups in Ringer's lactate Solution.