K
Kai Zhang
Researcher at Chinese Academy of Sciences
Publications - 181
Citations - 9524
Kai Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Optogenetics. The author has an hindex of 36, co-authored 150 publications receiving 6622 citations. Previous affiliations of Kai Zhang include Howard Hughes Medical Institute & Capital Normal University.
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Journal ArticleDOI
Gctf: Real-time CTF determination and correction
TL;DR: The main target of Gctf is to maximize the cross-correlation of a simulated CTF with the logarithmic amplitude spectra of observed micrographs after background subtraction to improve CTF parameters of all particles for subsequent image processing.
Posted ContentDOI
Gctf: real-time CTF determination and correction
TL;DR: Based on the global CTF determination, the local defocus for each particle and for single frames of movies is accurately refined, which improves CTF parameters of all particles for subsequent image processing.
Journal ArticleDOI
Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport
Keith A. Vossel,Kai Zhang,Jens Brodbeck,Aaron C. Daub,Punita Sharma,Steven Finkbeiner,Bianxiao Cui,Lennart Mucke +7 more
TL;DR: A mechanism for the protective effects of tau reduction in mouse models of Alzheimer’s disease is identified, and it is shown that Aβ requires tau to impair axonal transport, and t Tau reduction protects against Aβ-induced axonal Transport defects.
Journal ArticleDOI
The structure of the dynactin complex and its interaction with dynein
Linas Urnavicius,Kai Zhang,Aristides G. Diamant,Carina Motz,Max A. Schlager,Minmin Yu,Nisha A. Patel,Carol V. Robinson,Andrew P. Carter +8 more
TL;DR: The reconstruction reveals how dynactin is built around a filament containing eight copies of the actin-related protein Arp1 and one of β-actin, which is capped at each end by distinct protein complexes, and its length is defined by elongated peptides that emerge from the α-helical shoulder domain.
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Continuous distribution of emission states from single CdSe/ZnS quantum dots.
TL;DR: The photoluminescence dynamics of colloidal CdSe/ZnS/streptavidin quantum dots were studied using time-resolved single-molecule spectroscopy and autocorrelation analysis of lifetime and intensity fluctuations showed a nonlinear correlation between them.