K
Kaia Palm
Researcher at Tallinn University of Technology
Publications - 30
Citations - 3370
Kaia Palm is an academic researcher from Tallinn University of Technology. The author has contributed to research in topics: Alternative splicing & Epitope. The author has an hindex of 13, co-authored 25 publications receiving 3125 citations. Previous affiliations of Kaia Palm include Uppsala University & University of Helsinki.
Papers
More filters
Journal ArticleDOI
Mouse and rat BDNF gene structure and expression revisited
TL;DR: It is shown that kainic acid‐induced seizures that lead to changes in cellular Ca2+ levels as well as inhibition of DNA methylation and histone deacetylation contribute to the differential regulation of the expression of BDNF transcripts.
Journal ArticleDOI
Multiple promoters direct tissue-specific expression of the rat BDNF gene
Tõnis Timmusk,Tõnis Timmusk,Kaia Palm,Kaia Palm,Madis Metsis,Madis Metsis,Tõnu Reintam,Viiu Paalme,Mart Saarma,Mart Saarma,Håkan Persson +10 more
TL;DR: The data demonstrate that alternative usage of four promoters within the BDNF gene and differential splicing control tissue-specific and seizure-induced expression of BDNF mRNA.
Journal ArticleDOI
Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
TL;DR: It is shown that BDNF and antiBD NF transcripts form dsRNA duplexes in the brain in vivo, suggesting an important role for antiBDNF in regulating BDNF expression in human.
Journal ArticleDOI
Neuronal Expression of Zinc Finger Transcription Factor REST/NRSF/XBR Gene
TL;DR: It is shown that, although REST/NRSF/XBR expression decreases during neuronal development, it proceeds in the adult nervous system and counteracts with positive regulators to modulate target gene expression quantitatively in different cell types, including neurons.
Journal ArticleDOI
Neuron-specific splicing of zinc finger transcription factor REST/NRSF/XBR is frequent in neuroblastomas and conserved in human, mouse and rat.
TL;DR: In this paper, the structure of the REST/NRSF/XBR gene and its regulation by neuron-specific splicing is conserved in human, mouse, and rat.