K
Kaibin Zhu
Researcher at Harbin Medical University
Publications - 16
Citations - 149
Kaibin Zhu is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Medicine & Lung cancer. The author has an hindex of 4, co-authored 9 publications receiving 69 citations.
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Journal ArticleDOI
Simvastatin Suppresses Proliferation and Migration in Non-small Cell Lung Cancer via Pyroptosis.
Fengjiao Wang,Wei Liu,Jinfeng Ning,Junfeng Wang,Yaoguo Lang,Xiangyuan Jin,Kaibin Zhu,Xiuyun Wang,Xiaoguang Li,Fan Yang,Jianqun Ma,Shidong Xu +11 more
TL;DR: The results of this study showed that the antihyperlipidemic drug simvastatin induced pyroptosis in non-small cell lung cancer (NSCLC) cell lines and a xenograft mouse model, and inhibition of pyroPTosis attenuated the effects of simVastatin on tumor cell viability and migration.
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Musashi1 Promotes Non-Small Cell Lung Carcinoma Malignancy and Chemoresistance via Activating the Akt Signaling Pathway.
Yaoguo Lang,Xianglong Kong,Changjun He,Fengjiao Wang,Benkun Liu,Shibo Zhang,Jinfeng Ning,Kaibin Zhu,Shidong Xu +8 more
TL;DR: The role of Musashi1 (MSI1) in NSCLC malignancy and chemoresistance was investigated and it was demonstrated that MSI1 was able to promote the proliferation and glucose metabolism ofNSCLC cells, and to mediate the sensitivity to chemotherapy drugs in NSC cells.
Journal ArticleDOI
Placental Growth Factor Mediates Crosstalk Between Lung Cancer Cells and Tumor-Associated Macrophages in Controlling Cancer Vascularization and Growth.
Changjun He,Kaibin Zhu,Xue Bai,Yingbin Li,Dawei Sun,Yaoguo Lang,Jinfeng Ning,Fenglin Sun,Changfa Qu,Shidong Xu +9 more
TL;DR: The cross-talk between TAM and NSCLC cells via PLGF/Flt-1 and TGFβ receptor signaling may promote the growth and vascularization ofNSCLC.
Journal ArticleDOI
Constructing a global transcriptional regulatory landscape for early non-small cell lung cancer to identify hub genes and key pathways
TL;DR: By carrying out a series of in-depth analyses, hub genes and key pathways associated with early NSCLC were identified by a global transcriptional regulatory landscape.
Journal ArticleDOI
Runt-related transcription factor 1 contributes to lung cancer development by binding to tartrate-resistant acid phosphatase 5.
Changjun He,Xue Bai,Yingbin Li,Haobo Sun,Xianglong Kong,Bicheng Fu,Lantao Chen,Kaibin Zhu,Peng-Ju Li,Shidong Xu +9 more
TL;DR: The results of xenograft tumor in nude mice showed that silencing ACP5 could inhibit the growth of LC cells in vivo, and silenced RUNX1 inhibits LC progression through the ERK/MAPK axis by binding toACP5.