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Kalman Kovacs

Researcher at University of Toronto

Publications -  563
Citations -  19404

Kalman Kovacs is an academic researcher from University of Toronto. The author has contributed to research in topics: Adenoma & Pituitary adenoma. The author has an hindex of 70, co-authored 562 publications receiving 18382 citations. Previous affiliations of Kalman Kovacs include Institute for Social Security and Services for State Workers & St. Michael's GAA, Sligo.

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Microadenomas of the pituitary and abnormal sellar tomograms in an unselected autopsy series.

TL;DR: PROLACTIN-SECRETING microadenomas of the pituitary gland have been diagnosed on the basis of elevated serum prolactin concentrations and abnormal tomograms of the sella turcica.
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Pathology of invasive pituitary tumors with special reference to functional classification

TL;DR: It is concluded that immunocytochemical and ultrastructural characteristics of pituitary adenomas reflect the tendency of these tumors to infiltrate and hence may be of prognostic significance.
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Somatotroph Hyperplasia: SUCCESSFUL TREATMENT OF ACROMEGALY BY REMOVAL OF A PANCREATIC ISLET TUMOR SECRETING A GROWTH HORMONE-RELEASING FACTOR

TL;DR: Elevated serum GH and somatomedin C levels in a patient with an enlarged sella turcica and the characteristic responses seen in acromegaly to TRH, dopamine, and glucose do not occur exclusively in patients with discrete pituitary tumors and acromegalic, so consideration of ectopic GRF secretion should be made.
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p53 Expression in Pituitary Adenomas and Carcinomas: Correlation with Invasiveness and Tumor Growth Fractions

TL;DR: Conclusive nuclear immunopositivity for p53 was identified in a total of 12 tumors, all being either invasive adenomas or primary pituitary carcinomas, indicating that p53 expression, when conclusively present in pituitARY tumors, may be of some diagnostic usefulness as a marker of biologically aggressive behavior.