K
Kanumuri Siva Rama Raju
Researcher at Central Drug Research Institute
Publications - 43
Citations - 951
Kanumuri Siva Rama Raju is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Bioavailability & Pharmacokinetics. The author has an hindex of 17, co-authored 41 publications receiving 751 citations. Previous affiliations of Kanumuri Siva Rama Raju include Academy of Scientific and Innovative Research.
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Journal ArticleDOI
Comparative assessment of bioanalytical method validation guidelines for pharmaceutical industry
Naveen Kadian,Kanumuri Siva Rama Raju,Mamunur Rashid,Mohd Yaseen Malik,Isha Taneja,Muhammad Wahajuddin +5 more
TL;DR: The present review highlights the variations, similarities and comparison between bioanalytical method validation guidelines issued by major regulatory authorities worldwide.
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Synthesis and Insight into the Structure–Activity Relationships of Chalcones as Antimalarial Agents
Narender Tadigoppula,Venkateswarlu Korthikunta,Shweta Gupta,Papireddy Kancharla,Tanvir Khaliq,Awakash Soni,Rajeev Kumar Srivastava,Kumkum Srivastava,Sunil Kumar Puri,Kanumuri Siva Rama Raju,Wahajuddin,Puran Singh Sijwali,Vikash Kumar,Imran Siddiqi Mohammad +13 more
TL;DR: Licochalcone A (I), isolated from the roots of Chinese licorice, is the most promising antimalarial compound reported so far and two similar chalcones, medicagenin (II) and munchiwarin (III), from Crotalaria medicagenia, which exhibitedAntimalarial activity against Plasmodium falciparum .
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Pharmacokinetics study of arteether loaded solid lipid nanoparticles: An improved oral bioavailability in rats
Pankaj Dwivedi,Renuka Khatik,Kiran Khandelwal,Isha Taneja,Kanumuri Siva Rama Raju,Wahajuddin,Sarvesh Paliwal,Anil Kumar Dwivedi,Prabhat Ranjan Mishra +8 more
TL;DR: From the results, it can be concluded that ART-SLN offers a new approach to improve the oral bioavailability of ART and may help to protect the acid degradation of ART in stomach.
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Antileishmanial Activity of Pyrazolopyridine Derivatives and Their Potential as an Adjunct Therapy with Miltefosine.
Devireddy Anand,Pawan Kumar Yadav,Om P. S. Patel,Naveen Parmar,Rahul K. Maurya,Preeti Vishwakarma,Kanumuri Siva Rama Raju,Isha Taneja,Muhammad Wahajuddin,Susanta Kar,Prem P. Yadav +10 more
TL;DR: Investigating the effect of 6j on Leishmania promastigotes revealed that it induced molecular events, such as a loss in mitochondrial membrane potential, externalization of phosphatidylserine, and DNA fragmentation, that ultimately resulted in the programmed cell death of the parasite.
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Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents.
Om P. S. Patel,Akansha Mishra,Ranjani Maurya,Deepika Saini,Jyotsana Pandey,Isha Taneja,Kanumuri Siva Rama Raju,Sanjeev Kanojiya,Sanjeev K. Shukla,Mahendra Nath Srivastava,Muhammad Wahajuddin,Akhilesh K. Tamrakar,Arvind K. Srivastava,Prem P. Yadav +13 more
TL;DR: Koenidine (4) was identified as a metabolically stable antidiabetic compound, when evaluated in a rodent type 2 model, and showed a considerable reduction in the postprandial blood glucose profile with an improvement in insulin sensitivity.