K
Kao Jean Huang
Researcher at National Cheng Kung University
Publications - 29
Citations - 2186
Kao Jean Huang is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Dengue virus & Dengue fever. The author has an hindex of 17, co-authored 29 publications receiving 1989 citations. Previous affiliations of Kao Jean Huang include Pasteur Institute.
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Journal ArticleDOI
An interferon-γ-related cytokine storm in SARS patients
TL;DR: It is concluded that an interferon‐γ‐related cytokineStorm was induced post SARS coronavirus infection, and this cytokine storm might be involved in the immunopathological damage in SARS patients.
Journal ArticleDOI
Dengue Hemorrhagic Fever in Infants: A Study of Clinical and Cytokine Profiles
Nguyen Thanh Hung,Huan Yao Lei,Nguyen Trong Lan,Yee Shin Lin,Kao Jean Huang,Le Bich Lien,Chiou Feng Lin,Trai Ming Yeh,Do Quang Ha,Vu Thi Que Huong,Lien Cheng Chen,Jyh Hsiung Huang,Lam Thi My,Ching Chuan Liu,Scott B. Halstead +14 more
TL;DR: The present study is the first to report evidence of production of cytokines in infants with DHF/DSS and to describe the difference between the cytokine profile of infants with primary dengue virus infections and children with secondary infections.
Journal ArticleDOI
Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema.
Shih Min Wang,Huan Yao Lei,Kao Jean Huang,Jing-Ming Wu,Jen Ren Wang,Chun Keung Yu,Ih-Jen Su,Ching Chuan Liu +7 more
TL;DR: An extensive peripheral and central nervous system inflammatory response with abnormal IL-10, IL-13, and IFN-gamma cytokine production and lymphocyte depletion appears to be responsible for the pathogenesis of EV71-associated PE.
Journal ArticleDOI
The dual-specific binding of dengue virus and target cells for the antibody-dependent enhancement of dengue virus infection.
Kao Jean Huang,Yu-Ching Yang,Yee Shin Lin,Jyh-Hsiung Huang,Hsiao Sheng Liu,Trai Ming Yeh,Shun Hua Chen,Ching Chuan Liu,Huan Yao Lei +8 more
TL;DR: A novel mechanism of anti-prM Ab-mediated enhancement on d Dengue virus infection was found to be mediated by dual specific binding to dengue virion and to target cells, in addition to the traditional enhancement on FcR-bearing cells.
Journal ArticleDOI
Manifestation of thrombocytopenia in dengue-2-virus-infected mice.
Kao Jean Huang,Shu-Yi J. Li,Shiour-Ching Chen,Hsiao Sheng Liu,Yee Shin Lin,Trai Ming Yeh,Ching Chuan Liu,Huan Yao Lei +7 more
TL;DR: This dengue-2-virus-infected mouse system accompanied by thrombocytopenia and anti-platelet antibody will be a valuable model to study the pathogenicity of d Dengue virus infection.