K
Kaori Yoshida
Researcher at Niigata University
Publications - 19
Citations - 624
Kaori Yoshida is an academic researcher from Niigata University. The author has contributed to research in topics: Cytokine & Myocarditis. The author has an hindex of 13, co-authored 19 publications receiving 588 citations. Previous affiliations of Kaori Yoshida include RMIT University.
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Journal ArticleDOI
Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats.
He Chang,Haruo Hanawa,Hui Liu,Tsuyoshi Yoshida,Manabu Hayashi,Ritsuo Watanabe,Satoru Abe,Ken Toba,Kaori Yoshida,Raafat Elnaggar,Shiro Minagawa,Yuji Okura,Kiminori Kato,Makoto Kodama,Hiroki Maruyama,Jun-ichi Miyazaki,Yoshifusa Aizawa +16 more
TL;DR: Results showed that the expression of immunologic molecules in IL-1-stimulated NC cells was significantly decreased by rIL-22 or serum containing IL-22-Ig, and the reason for this effectiveness may be that IL- 22 suppressed gene expression of PG synthases, IL-6, and chemokines in activated NC noninflammatory cells.
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Lipocalin-2/Neutrophil Gelatinase-B Associated Lipocalin Is Strongly Induced in Hearts of Rats With Autoimmune Myocarditis and in Human Myocarditis
Limin Ding,Haruo Hanawa,Yoshimi Ota,Go Hasegawa,Kazuhisa Hao,Fuyuki Asami,Ritsuo Watanabe,Tsuyoshi Yoshida,Ken Toba,Kaori Yoshida,Minako Ogura,Makoto Kodama,Yoshifusa Aizawa +12 more
TL;DR: Cardiomyocytes, vascular wall cells and fibroblasts in myocarditis strongly express Lcn2/NGAL via proinflammatory cytokines, and high levels were initially sustained during the inflammatory stage, then decreased with recovery.
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Expression of the peptide hormone hepcidin increases in cardiomyocytes under myocarditis and myocardial infarction
Manabu Isoda,Haruo Hanawa,Ritsuo Watanabe,Tsuyoshi Yoshida,Ken Toba,Kaori Yoshida,Mayuko Kojima,Keita Otaki,Kazuhisa Hao,Limin Ding,Komei Tanaka,Tsugumi Takayama,Kiminori Kato,Yuji Okura,Makoto Kodama,Yoshimi Ota,Jun-ichi Hayashi,Yoshifusa Aizawa +17 more
TL;DR: Cardiac expression of hepcidin is strongly induced in cardiomyocytes under myocarditis and MI, conditions in which inflammatory cytokine levels increase and may play an important role in iron homeostasis and free radical generation.
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Spatiotemporal changes of coxsackievirus and adenovirus receptor in rat hearts during postnatal development and in cultured cardiomyocytes of neonatal rat.
Takeshi Kashimura,Makoto Kodama,Yuko Hotta,Junichi Hosoya,Kaori Yoshida,Takuya Ozawa,Ritsuo Watanabe,Yuji Okura,Kiminori Kato,Haruo Hanawa,Ryozo Kuwano,Yoshifusa Aizawa +11 more
TL;DR: Examination of expression levels of CAR in rat hearts found that CAR decreased gradually during postnatal development, although CAR was detectable, even in adults, and immunohistochemistry revealed CAR on the whole surface of cardiomyocytes in immature rat hearts.
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Alteration of IL-17 related protein expressions in experimental autoimmune myocarditis and inhibition of IL-17 by IL-10-Ig fusion gene transfer.
He Chang,Haruo Hanawa,Tsuyoshi Yoshida,Manabu Hayashi,Hui Liu,Limin Ding,Keita Otaki,Kazuhisa Hao,Kaori Yoshida,Kiminori Kato,Ken Toba,Makoto Kodama,Hiroki Maruyama,Jun-ichi Miyazaki,Yoshifusa Aizawa +14 more
TL;DR: IL-17 is highly produced by αβT cells in the early phase of EAM hearts and IL-17 inhibition might be a possible mechanism of the amelioration of E AM by IL-10-Ig treatment, suggesting that IL- 17 produced by Th17 plays an important role in the pathogenesis of rat EAM.