K
Kaoru Onozato
Researcher at National Defense Medical College
Publications - 5
Citations - 985
Kaoru Onozato is an academic researcher from National Defense Medical College. The author has contributed to research in topics: Cancer & Fluorescence in situ hybridization. The author has an hindex of 5, co-authored 5 publications receiving 904 citations. Previous affiliations of Kaoru Onozato include National Cancer Research Institute.
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Journal ArticleDOI
Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions
TL;DR: TR play a role in controlling the immune response against pancreatic ductal carcinoma from the premalignant stage to established cancer, and a high prevalence of TR seems to be a marker of poor prognosis.
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Expression and Gene Amplification of Actinin-4 in Invasive Ductal Carcinoma of the Pancreas
Satoru Kikuchi,Kazufumi Honda,Hitoshi Tsuda,Nobuyoshi Hiraoka,Issei Imoto,Tomoo Kosuge,Tomoko Umaki,Kaoru Onozato,Miki Shitashige,Umio Yamaguchi,Masaya Ono,Akihiko Tsuchida,Tatsuya Aoki,Johji Inazawa,Setsuo Hirohashi,Tesshi Yamada +15 more
TL;DR: Recurrent amplification of chromosome 19q13.1-2 has been reported in pancreatic cancer, but the exact target gene has not been identified and actinin-4 contributes to the invasive growth of pancreatic ductal carcinoma, and ACTN4 is one of the candidate oncogenes in this chromosome locus.
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Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance
Sohei Yamamoto,Hitoshi Tsuda,Kazufumi Honda,Kaoru Onozato,Masashi Takano,Seiichi Tamai,Issei Imoto,Johji Inazawa,Tesshi Yamada,Osamu Matsubara +9 more
TL;DR: The actinin-4 gene may be a target of the 19q amplicon, acting as a candidate oncogene, and serve as a predictor of poor outcome and tumor chemoresistance in patients with advanced-stage ovarian cancers.
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Solid-pseudopapillary neoplasms of the pancreas in men and women: Do they differ?
Yu Takahashi,Nobuyoshi Hiraoka,Kaoru Onozato,Tatsuhiro Shibata,Tomoo Kosuge,Yuji Nimura,Yae Kanai,Setsuo Hirohashi +7 more
TL;DR: It is suggested that SPNs in men tend to be a solid mass with slower progression of degenerative changes during their growth compared to that in women, which allows male SPNs to be correctly diagnosed despite their less typical features.
Journal ArticleDOI
Therapeutic effect of edaravone on inner ear barotrauma in the guinea pig.
Hitoshi Maekawa,Takeshi Matsunobu,Hitoshi Tsuda,Kaoru Onozato,Yukihiro Masuda,Tetsuya Tanabe,Akihiro Shiotani +6 more
TL;DR: Results strongly suggest that ROS is produced in the cochlea in response to acute pressure changes and that ROS plays an important role in the pathophysiology of IEB.